ANAGYRINE Chemical Properties

alpha 

D25 -168° (c = 4.8 in ethanol)

Boiling point:

bp4 210-215°; bp12 260-270°

Density 

1.22±0.1 g/cm3 (20 ºC 760 Torr)

refractive index 

1.6280 (estimate)

storage temp. 

Store at -20°C

solubility 

DMSO: soluble,Methanol: soluble

form 

Cryst.

pka

9.71±0.20(Predicted)

CAS DataBase Reference

486-89-5

ANAGYRINE Usage And Synthesis

Description

An amorphous alkaloid isolated from Thermopsis rhombifolia (Watt), Richards, and also present in Lupinus macounii Rydb. The base forms a perchlorate, m.p. 313°C and a picrate, m.p. 253°C. On catalytic hydrogenation it yields the octahydro derivative, b.p. l40°CjO.2 mm which also forms a perchlorate, m.p. 213°C; [α]_D - 40.9° (H20).

Uses

Anagyrine is a naturally occuring alkaloid found in Genista vuralli, which displays antimicrobial activity.

target

Antifection

References

Manske, Marion., Can. J. Res., 20B, 265 (1942)
Manske, Marion., ibid, 21B, 144 (1943)

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