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ANAGYRINE

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ANAGYRINE Basic information

Product Name:
ANAGYRINE
Synonyms:
  • ANAGYRINE
  • RHOMBININE
  • 3,4,5,6-Tetradehydrospartein-2-one
  • 7,14-Methano-4H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-4-one, 7,7a,8,9,10,11,13,14-octahydro-, [7R-(7alpha,7abeta,14alpha)]-
  • Anagyrin
  • Monolupin
  • Monolupine
  • Rhombinin
CAS:
486-89-5
MF:
C15H20N2O
MW:
244.33
Product Categories:
  • Alkaloids
Mol File:
486-89-5.mol
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ANAGYRINE Chemical Properties

alpha 
D25 -168° (c = 4.8 in ethanol)
Boiling point:
bp4 210-215°; bp12 260-270°
Density 
1.22±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 
1.6280 (estimate)
storage temp. 
Store at -20°C
solubility 
DMSO: soluble,Methanol: soluble
form 
Cryst.
pka
9.71±0.20(Predicted)
color 
Colorless to light yellow
CAS DataBase Reference
486-89-5
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ANAGYRINE Usage And Synthesis

Description

An amorphous alkaloid isolated from Thermopsis rhombifolia (Watt), Richards, and also present in Lupinus macounii Rydb. The base forms a perchlorate, m.p. 313°C and a picrate, m.p. 253°C. On catalytic hydrogenation it yields the octahydro derivative, b.p. l40°CjO.2 mm which also forms a perchlorate, m.p. 213°C; [α]D - 40.9° (H20).

Uses

Anagyrine is a naturally occuring alkaloid found in Genista vuralli, which displays antimicrobial activity.

target

Antifection

References

Manske, Marion., Can. J. Res., 20B, 265 (1942)
Manske, Marion., ibid, 21B, 144 (1943)

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