(S)-(+)-KETOPINIC ACID Chemical Properties

Melting point:

237-239 °C(lit.)

alpha 

58 º (C=1 IN CHLOROFORM)

Boiling point:

313.3±25.0 °C(Predicted)

Density 

1.238±0.06 g/cm3(Predicted)

refractive index 

25.5 ° (C=0.65, MeOH)

storage temp. 

Sealed in dry,Room Temperature

form 

powder to crystal

pka

3.67±0.40(Predicted)

color 

White to Almost white

optical activity

[α]23/D +58°, c = 1 in chloroform

BRN 

4180005

CAS DataBase Reference

40724-67-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

2918300090

(S)-(+)-KETOPINIC ACID Usage And Synthesis

Uses

7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxylic Acid is a useful reactant for the preparation of alkenyl nitrile electrophiles for the possible use of covalent protein labeling.

Uses

(1S)-(+)-Ketopinic acid may be used to prepare:

• Chiral phosphine-oxazoline ligands, which can used in asymmetric palladium-catalyzed Heck reaction of aryl or alkenyl triflates with cyclic alkenes.
• A chiral imino-phosphine ligand, which can be used in palladium-catalyzed asymmetric Diels–Alder reactions to prepare six-membered carbocycles.
• A chiral iminopyridine ligand, which can be used in copper-catalyzed Henry (nitro aldol) reaction between nitromethane and o-anisol to form the corresponding β-hydroxynitroalkane.

Uses

7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxylic Acid is a useful reactant for the preparation of alkenyl nitrile electrophiles for the possible use of covalent protein labeling.

General Description

(1S)-(+)-Ketopinic acid is a chiral ketone.

(S)-(+)-KETOPINIC ACID(40724-67-2)Related Product Information

• Bicyclo[2.2.1]heptane-1-carboxylic acid, 7,7-dimethyl-2-oxo-
• (1R)-(-)-Ketopinic acid
• (S)-2-HYDROXYMETHYLCYCLOHEXANONE
• AKOS BBS-00001903
• 3-BROMO-7,7-DIMETHYL-2-OXOBICYCLO[2.2.1]HEPTANE-1-CARBOXYLIC ACID
• (S)-(+)-KETOPINIC ACID