Basic information Safety Supplier Related

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Basic information Safety Supplier Related

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Basic information

Product Name:
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Synonyms:
  • 3-SN-PHOSPHATIDYLCHOLINE, 1,2-DIOLEOYL
  • 1,2-DI9-CIS-OCTADECENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 1,2-DI(CIS-9-OCTADECENOYL)-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE
  • 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 18:1 PC (CIS)
  • Dierucoyl phosphatidylcholine
  • COATSOME MC-8181 (DOPC)
CAS:
4235-95-4
MF:
C44H84NO8P
MW:
786.12
EINECS:
224-193-8
Mol File:
4235-95-4.mol
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1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties

Melting point:
-21 °C
storage temp. 
-20°C
solubility 
Chloroform (Slightly, Sonicated), Methanol (Slightly)
form 
solution
color 
White to Off-White
BRN 
3898070
Stability:
Hygroscopic, Light Sensitive
InChIKey
SNKAWJBJQDLSFF-NVKMUCNASA-N
SMILES
[C@H](OC(=O)CCCCCCC/C=C\CCCCCCCC)(COP([O-])(=O)OCC[N+](C)(C)C)COC(=O)CCCCCCC/C=C\CCCCCCCC |&1:0,r|
CAS DataBase Reference
4235-95-4
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-38-40-48/20/22-36/38-20/22-63
Safety Statements 
36/37-26
RIDADR 
UN 1888 6.1/PG 3
WGK Germany 
3
8-10-23
HS Code 
29232000

MSDS

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1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Usage And Synthesis

Description

DOPC, also known as 18:1 (?9-Cis) PC, is a phospholipid containing the unsaturated long-chain (18:1) oleic acid inserted at the sn-1 and sn-2 positions. It is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes.

Chemical Properties

Amorphous white powder

Uses

1,2-Dioleoyl-sn-glycero-3-phosphocholine has been used for the reconstitution of proteoliposome (PL). It has also been used in the preparation of lipid vesicles.

Uses

18:1 (Δ9-Cis) PC (DOPC) has been used for reproducing the supramolecular structure of the synovial fluid. It may also be used in the liposome preparation and in the preparation of planar supported membranes.

Uses

1,2-Dioleoyl-sn-glycero-3-phosphocholine is a phospholipid containing the unsaturated long-chain (18:1) oleic acid inserted at the sn-1 and sn-2 positions. It is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes.

Definition

ChEBI: 1,2-dioleoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine 36:2 in which the phosphatidyl acyl groups at positions 1 and 2 are both oleoyl. It is a 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine betaine and a 1,2-di-octadecenoyl-sn-glycero-3-phosphocholine. It is functionally related to an oleic acid. It is a conjugate base of a 1,2-dioleoyl-sn-glycero-3-phosphocholine(1+).

General Description

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Biochem/physiol Actions

18:1 (Δ9-Cis) PC (DOPC) shows high resistance to the toxic effects of dimethyl sulfoxide (DMSO).

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINESupplier

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