1-OLEOYL-2-ACETYL-SN-GLYCEROL Chemical Properties

Boiling point:

490.0±15.0 °C(Predicted)

Density 

0.980±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

ethanol: 20 mg/mL

form 

oil

pka

13.89±0.10(Predicted)

color 

yellow

BRN 

8168731

Stability:

Temperature Sensitive. This compound can rearrange to the 1,3-isomer in solution or during prolonged storage.

CAS DataBase Reference

86390-77-4(CAS DataBase Reference)

Safety Information

WGK Germany 

3

F 

10-23

MSDS

• Language:English Provider:SigmaAldrich

1-OLEOYL-2-ACETYL-SN-GLYCEROL Usage And Synthesis

Chemical Properties

Colourless to light yellow oil

Uses

Activator of phospholipid-dependent protein kinase C; and stimulator of secretion and aggregation in blood platelets.x

Uses

18:1-2:0 DG (1-oleoyl-2-acetyl-sn-glycerol) has been used as a diacyl glycerol (DAG) analog to test its impact on DAG-sensitive channels in thalamocortical (TC) neurons. It may be used as an internal standard for retention time calibration in ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOF MS)?for blood sample lipid quantification. It may also be used as a protein kinase C (PKC) activator in adrenal glands.

Definition

ChEBI: 1-Oleoyl-2-acetyl-sn-glycerol is a 1,2-diglyceride.

General Description

18:1-2:0 DG, also called 1-oleoyl-2-acetyl-sn-glycerol (OADG), is a synthetic analog of diacyl glycerol (DAG) and is membrane permeable.

Biochem/physiol Actions

1-Oleoyl-2-acetyl-sn-glycerol is a synthetic, cell permeable diacylglycerol analog. It is often used as an activator of calcium-dependent protein kinase C (PKC).

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