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Gatifloxacinacid

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Gatifloxacinacid Basic information

Product Name:
Gatifloxacinacid
Synonyms:
  • Gatifloxacinacid
  • 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(3-Methyl-1-piperazinyl)-4-oxo-, Monohydrochloride (9CI)
  • 3-Quinolinecarboxylicacid,1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(3-Methyl-1-piperazinyl)-4-oxo-,hydrochloride (1:1)
  • BMS 206584-01 hydrochloride
  • Gatifloxacin hydrochloride (AM 1155 hydrochloride
  • PD 135432 hydrochloride)
  • AM 1155 hydrochloride
  • AM 1155 HYDROCHLORIDE;BMS 206584-01 HYDROCHLORIDE;PD 135432 HYDROCHLORIDE
CAS:
121577-32-0
MF:
C19H22FN3O4.ClH
MW:
411.859
Mol File:
121577-32-0.mol
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Gatifloxacinacid Chemical Properties

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Soluble in DMSO
form 
Powder
color 
White to off-white
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Gatifloxacinacid Usage And Synthesis

Biological Activity

Gatifloxacin hydrochloride (AM-1155 hydrochloride) is a potent fluoroquinolone antibiotic with broad-spectrum antimicrobial activity.

in vivo

Gatifloxacin hydrochloride (subcutaneous injection; 100 mg/kg; 3 times a day; 30 days) significantly decreases the number of lesions in mouse footpad with Nocardia brasiliensis .

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Animal Model: Female BALB/c mice with Nocardia brasiliensis in the right hind footpad
Dosage: 100 mg/kg
Administration: Subcutaneous injection; 3 times a day; 30 days
Result: Reduced the production of lesions in mice.

target

Topoisomerase II

36.7 μM ()

GatifloxacinacidSupplier

ShangHai Caerulum Pharma Discovery Co., Ltd.
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