(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Chemical Properties

Melting point:

158-162°C

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

Powder

color 

white to pale yellow

Water Solubility 

Sparingly soluble in water.

CAS DataBase Reference

443347-10-2

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39-36

WGK Germany 

3

MSDS

• Language:English Provider:ALFA

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Usage And Synthesis

Chemical Properties

White solid

Uses

(S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine is used in Pharmaceutical and industry applications.

Uses

Ligand employed in the asymmetic hydrogenation of ?-keto esters, 2-arylacrylates, aryl ketones , and other substrates.

Reactions

1. Chiral ligand for the asymmetric hydrogenation of β-keto esters.
2. Chiral ligand for enantioselective rhodium-catalyzed [2+2+2] carbocyclization reactions.
3. Chiral ligand for ruthenium catalyzed hydrogenation of (E)-β-(acylamino)acrylates to β-amino acids.
4. The Rhodium complex gives higher enantioselectivity for hydrogenation of (Z)-β-(acylamino)acrylates to β-amino acids.
5. Chiral ligand for copper-catalyzed asymmetric hydrosilylation of ketones.
6. Chiral ligand for asymmetric allylic substitution reactions using boronic acids as nucleophiles.
7. Gives useful selectivity in asymmetric Pauson-Khand-type cyclizations.

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE(443347-10-2)Related Product Information

• (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE