Basic information Reactions Safety Supplier Related

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE

Basic information Reactions Safety Supplier Related

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Basic information

Product Name:
(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE
Synonyms:
  • CTH-(R)-XYLYL-P-PHOS
  • CTH-(S)-XYLYL-P-PHOS
  • (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE
  • (S)-(-)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE
  • (R)-XYLYL-P-PHOS
  • (S)-XYLYL-P-PHOS
  • (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS&
  • min.cth-(r)-xylyl-p-phos
CAS:
442905-33-1
MF:
C46H50N2O4P2
MW:
756.85
Mol File:
442905-33-1.mol
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(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Chemical Properties

Melting point:
190-194°C
Boiling point:
791.1±60.0 °C(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-1.76±0.38(Predicted)
form 
Powder
color 
white to pale yellow
optical activity
[α]20/D +125°, c = 1 in chloroform
Water Solubility 
Sparingly soluble in water.
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39-36
WGK Germany 
3

MSDS

  • Language:English Provider:ALFA
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(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Usage And Synthesis

Reactions

  1. Chiral ligand for ruthenium- catalyzed asymmetric hydrogenation of aromatic ketones.
  2. Chiral ligand for iridium-catalyzed asymmetric hydrogenation of quinolines.
  3. Chiral ligand for copper- catalyzed asymmetric hydrosilylation of ketones.
  4. Synthesis of new chiral 2-functionized-1,2,3,4-tetrahydroquinoline derivatives via asymmetric hydrogenation of substituted quinolines.
  5. Rhodium-biphosphine-catalyzed asymmetric, intermolecular hydroheteroarylation of α-substituted acrylate derivatives.

Chemical Properties

White solid

Uses

(R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine is used in asymmetric hydrogenation.It acts as a ligand used in the asymmetic hydrogenation of β-keto esters, 2-arylacrylates, aryl ketones , and other substrates. Other applications include it is used widely as a Catalyst, when combined with Rh, Ru and Ir precursor.

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINESupplier

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