4-Hydroxy Valsartan, Mixture of Diastereomers
4-Hydroxy Valsartan, Mixture of Diastereomers Basic information
- Product Name:
- 4-Hydroxy Valsartan, Mixture of Diastereomers
- Synonyms:
-
- (S)-2-{(4(R,S)-Hydroxy-pentanoyl)-[2(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]amino}-3-methyl-butyric Acid
- 4-Hydroxy Valsartan, Mixture of Diastereomers
- CGP 71580
- N-(4-Hydroxy-1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
- Valsartan 4-Hydroxy
- (S)-N-(4-Hydroxy-1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-valine
- (2S)-2-(N-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-hydroxypentanamido)-3-methylbutanoic acid
- Valsartan 4-Hydroxy Impurity
- CAS:
- 188259-69-0
- MF:
- C24H29N5O4
- MW:
- 451.52
- Product Categories:
-
- Intermediates & Fine Chemicals
- Metabolites
- Pharmaceuticals
- Mol File:
- 188259-69-0.mol
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4-Hydroxy Valsartan, Mixture of Diastereomers Chemical Properties
- Melting point:
- 130-132°C
- storage temp.
- Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- solubility
- Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
- CAS DataBase Reference
- 188259-69-0
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4-Hydroxy Valsartan, Mixture of Diastereomers Usage And Synthesis
Description
4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan . It reduces platelet aggregation induced by epinephrine and collagen but not ADP in human whole blood.
Chemical Properties
White Solid
Uses
A nonpeptide angiotensin II AT1-receptor antagonist.
Definition
ChEBI: 4-Hydroxyvalsartan is a valine derivative.
4-Hydroxy Valsartan, Mixture of DiastereomersSupplier
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4-Hydroxy Valsartan, Mixture of Diastereomers(188259-69-0)Related Product Information
- Isoleucine Valsartan
- Valsartan Desvaleryl Impurity
- Valsartan n-Propyl
- Valsartan Impurity 1
- Valsartan Impurity 26
- L-VALINE, N-[(2'-CYANO[1,1'-BIPHENYL]-4-YL)METHYL]-, METHYL ESTER, MONOHYDROCHLORIDE
- Valsartan
- Valsartan Impurity 5
- Valsartan Methyl Ester
- Pentanamide, N-(diazirino[1,3-f]phenanthridin-4-ylmethyl)-N-(2-methylpropyl)-
- Valsartan Impurity 12
- Valsartan Impurity 3
- ethyl N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-N-pentanoyl-L-valinate
- Valsartan Impurity 10
- 5-[2-(4'-METHYLBIPHENYL)]TETRAZOLE
- Valsartan Related Compound A
- Valsartan cyano analog methyl ester
- L-Valine, N-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-N-(1-oxopropyl)-, methyl ester