fumitremorgin B Chemical Properties

Melting point:

205-207 °C

Boiling point:

724.3±60.0 °C(Predicted)

Density 

1.35±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMSO: Soluble,Methanol: Soluble

form 

A solid

pka

10.74±0.60(Predicted)

fumitremorgin B Usage And Synthesis

Description

This tremorgenic alkaloid is highly toxic and is elaborated by Aspergillus jurnigatus. The structure given above has been determined from X-ray crystallography. The crystals are orthorhombic with space group P2 1212 1, a = 14.771, b = 24.925 and c = 7.321 A with Z = 4. The absolute configuration is based upon that of L( - )-proline formed by acid hydrolysis of the alkaloid.

Definition

ChEBI: An organic heteropentacyclic compound that is a mycotoxic indole alkaloid produced by several fungi via a tryptophan-proline diketopiperazine intermediate.

References

Yamazaki et al., Tetrahedron Lett., 27 (1975)

fumitremorgin B(12626-17-4)Related Product Information

• Fumitremorgin A
• tetrahydroharmine
• 5-(DIISOPROPYLAMINO)AMYLAMINE
• (1,4-DIMETHYL-2-PIPERAZINYL)METHANOL
• (R)-HEXAHYDROPYRROLO[1,2-A]PYRAZIN-1(2H)-ONE
• 6-Methoxytrytophol
• HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE
• 1-(1H-INDOL-3-YL)-ETHANOL
• 1-ISOPROPYL-PIPERAZIN-2-ONE
• 1-ISOPROPYL-2-METHYL-PIPERAZINE
• CYCLO(-GLY-TRP)
• 2-amino-1-(1H-indol-3-yl)ethanol
• CYCLO(-ALA-SER)
• CYCLO(-GLY-SER)
• fumitremorgin B
• CYCLO(-GLY-PRO)
• (S)-1-ISOPROPYL-2-METHYL-PIPERAZINE
• 3-PYRROLIDINO-1,2-PROPANEDIOL