Lensiprazine Chemical Properties

Boiling point:

668.5±55.0 °C(Predicted)

Density 

1.262

pka

12.51±0.40(Predicted)

Lensiprazine Usage And Synthesis

Uses

Lensiprazine is a potent dopamine D2 receptor (D2R) antagonist that acts as a serotonin reuptake inhibitor. Lensiprazine can be used to study bipolar disorder and schizophrenia[1][2][3].

References

[1] Bollu R, et al. Potential anti-proliferative agents from 1, 4-benzoxazinone-quinazolin-4 (3H)-one templates[J]. Bioorganic & Medicinal Chemistry Letters, 2017, 27(24): 5481-5484. DOI:10.1016/j.bmcl.2017.10.044
[2] Lange J H M, et al. Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugs[J]. Journal of medicinal chemistry, 2007, 50(21): 5103-5108. DOI:10.1021/jm070516u
[3] Rauly-Lestienne I, et al. Differential profile of typical, atypical and third generation antipsychotics at human 5-HT 7a receptors coupled to adenylyl cyclase: detection of agonist and inverse agonist properties[J]. Naunyn-Schmiedeberg's archives of pharmacology, 2007, 376: 93-105. DOI:10.1007/s00210-007-0182-6

Lensiprazine(327026-93-7)Related Product Information

• Basic Violet 1
• Methyl acrylate
• Propyl butyrate
• Indole-3-acetic acid
• Indole-3-butyric acid
• Methylparaben
• Kresoxim-methyl
• Methanol
• Indometacin
• Acetonitrile
• Propyl gallate
• Methyl
• 2H-1,4-BENZOXAZIN-3(4H)-ONE
• fluoro jade
• Lensiprazine