Basic information Safety Supplier Related

DOTARIZINE

Basic information Safety Supplier Related

DOTARIZINE Basic information

Product Name:
DOTARIZINE
Synonyms:
  • 1-(diphenylmethyl)-4-(3-(2-phenyl-1,3-dioxolan-2-yl)propyl)-piperazin
  • DOTARIZINE
  • 1-(DIPHENYLMETHYL)-4-[3-(2-PHENYL-1,3-DIOXOLAN-2-YL)]PIPERAZINE
  • 1-(DIPHENYLMETHYL)-4-[3-(2-PHENYL-1,3-DIOXOLAN-2-YL)PROPYL]-PIPERAZINE
  • Dotaricin
  • FI-6026
  • Piperazine, 1-(diphenylmethyl)-4-[3-(2-phenyl-1,3-dioxolan-2-yl)propyl]-
CAS:
84625-59-2
MF:
C29H34N2O2
MW:
442.59
Product Categories:
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
84625-59-2.mol
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DOTARIZINE Chemical Properties

Melting point:
100-1010C
form 
White to off-white solid.
color 
White Crystalline
CAS DataBase Reference
84625-59-2
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DOTARIZINE Usage And Synthesis

Chemical Properties

White Crystalline Solid

Uses

Antimigraine.

Definition

ChEBI: Dotarizine is an N-alkylpiperazine in which the two amino hydrogens of piperazine have been replaced by diphenylmethyl and 3-(2-phenyl-1,3-dioxolan-2-yl)propyl groups. A calcium channel blocker and serotonin (5-HT2) receptor antagonist used in the treatment of migraine. It has a role as a calcium channel blocker, a serotonergic antagonist and a vasodilator agent. It is a N-alkylpiperazine, a dioxolane and a cyclic ketal.

DOTARIZINESupplier

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