CARBAZOCHROME SODIUM SULFONATE TRIHYDRATE
CARBAZOCHROME SODIUM SULFONATE TRIHYDRATE Basic information
- Product Name:
- CARBAZOCHROME SODIUM SULFONATE TRIHYDRATE
- Synonyms:
-
- adrenochromemonosemicarbazonesodiumsalicylatecomplex
- statimo
- 1-METHYL-6-OXO-2,3,5,6-TETRAHYDROINDOLE-5-SEMICARBAZONO-2-SULFONIC ACID SODIUM SALT 3 HYDRATE
- CARBAZOCHROME SODIUM SULFONATE TRIHYDRATE
- CARBAZOCHROME SALICYLATE
- CARBAZOCHROME SODIUM
- adrenochrome semicarbazone salicylate
- adrenosem
- CAS:
- 13051-01-9
- MF:
- C10H17N4NaO8S
- MW:
- 376.32
- EINECS:
- 235-927-1
- Mol File:
- 13051-01-9.mol
CARBAZOCHROME SODIUM SULFONATE TRIHYDRATE Chemical Properties
- Melting point:
- 196-197.5° (dec)
CARBAZOCHROME SODIUM SULFONATE TRIHYDRATE Usage And Synthesis
Originator
Adrenosem,Beecham,US,1953
Manufacturing Process
A suspension containing 1 part by weight of adrenalin and 2 to 6 parts by weight of silver oxide in 150 to 250 parts by weight of methanol or ethanol is stirred for about 10 minutes. The alcoholic adrenochrome solution obtained is separated by draining and the filtrate is quickly evaporated to dryness at low temperature and in vacuo. The red crystals of adrenochrome obtained are dissolved in 45 to 55 parts by weight of water. To this solution, 2 parts of sodium acetate dissolved in 2 to 3 parts of water and 2 parts of semicarbazide hydrochloride dissolved in 2 to 3 parts of water are added. The formed precipitate consisting of red-orange prismatic needles is separated by filtration and recrystallized from diluted ethanol. There is obtained 0.30 to 0.40 part by weight of adrenochrome monosemicarbazone dihydrate, melting at 203°C with decomposition.
Therapeutic Function
Hemostatic
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