RAT IL-6
RAT IL-6 Chemical Properties
- storage temp.
- −20°C
- form
- buffered aqueous solution
- biological source
- rat
MSDS
- Language:English Provider:SigmaAldrich
RAT IL-6 Usage And Synthesis
Biochem/physiol Actions
Interleukin-6 (IL-6) is a multifunctional protein originally discovered in the media of cells stimulated with double stranded RNA. IL-6 appears to be directly involved in the responses that occur after infection and injury and may prove to be as important as IL-1 and TNF-α in regulating the acute phase response. IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. IL-6 induces multiple effects, as indicated by its numerous synonyms: plasmacytoma growth factor (PCT-GF), interferon-β-2 (IFN-β2), monocyte derived human B cell growth factor, B cell stimulating factor (BSF-2), hepatocyte stimulating factor (HSF), Interleukin Hybridoma/Plasmacytoma-1 (IL-HP1). In addition, IL-6 appears to interact with IL-2 in the proliferation of T lymphocytes. IL-6 also potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors.
Description
Interleukin-6 Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 187 amino acids and having a molecular mass of 21732 Dalton.
The IL6 is purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
Interleukin-6 is a potent pro-inflammatory cytokine primarily produced by activated T cells and an assortment of other cells including endothelial cells and macrophages. IL-6 affects B and T lymphocytes and has been shown to have a role in host defense, acute phase reactions, immune responses and hematopoiesis.
RAT IL-6Supplier
- Tel
- 021-60514606 18321282235
- sale1@shybsw.net
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Tel
- 021-61998208 18217752821
- sales@klbio.cn
- Tel
- 021-38015121 18438616290
- lanwu@univ-bio.com