RAT IL-4 Chemical Properties

storage temp. 

−20°C

form 

lyophilized powder

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

RAT IL-4 Usage And Synthesis

Description

Interleukin-4 Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 125 amino acids and having a molecular mass of 14kDa.
The IL-4 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

IL4 is a pleiotropic cytokine produced by activated T cells. IL4 is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. IL4, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

RAT IL-4()Related Product Information

• Recombinant Rat IL-9
• Recombinant Rat MANF
• Recombinant Rat LIX/CXCL5
• Recombinant Rat IP-10/CXCL10
• Recombinant Rat IL-5
• Recombinant Rat KGF-2/FGF-10
• Recombinant Rat IL-7
• Recombinant Rat Lymphotactin/XCL1
• RAT IL-6
• Recombinant Rat LIF