FTI-277
FTI-277 Basic information
- Product Name:
- FTI-277
- Synonyms:
-
- METHYL[N-[2-PHENYL-4-N-[2(R)-AMINO-3-MERCAPTOPROPYLAMINO] BENZOYL]]-METHIONATE, TFA
- FTI-277
- N-[4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE METHYL ESTER TRIFLUOROACETATE SALT
- N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt
- N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine methyl ester
- FTI-277;FTI277
- L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-, methyl ester
- CAS:
- 170006-73-2
- MF:
- C22H29N3O3S2
- MW:
- 447.61
- Mol File:
- 170006-73-2.mol
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FTI-277 Chemical Properties
- Boiling point:
- 684.2±55.0 °C(Predicted)
- Density
- 1.222±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- H2O: soluble
- form
- amorphous semi-solid
- pka
- 9.81±0.10(Predicted)
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MSDS
- Language:English Provider:SigmaAldrich
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FTI-277 Usage And Synthesis
Uses
Farnesyltransferase inhibitor 277 (FTI-277) has been used to:
- inhibit protein farnesylation in breast cell lines.
- in marrow-isolated adult multilineage inducible cells (MIAMI).
- inhibition of farnesyl transferase in CV-1 in Origin with SV40 genes cells (COS-7).
Biochem/physiol Actions
Farnesyltransferase inhibitor 277 (FTI-277) mediates apoptosis in multiple myeloma and is regarded as a potential therapeutic agent.
FTI-277Supplier
Shanghai Boyle Chemical Co., Ltd.
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- sales@boylechem.com
3B Pharmachem (Wuhan) International Co.,Ltd.
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- 821-50328103-801 18930552037
- 3bsc@sina.com
MedChemexpress LLC
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- 021-58955995
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AdooQ BioScience, LLC
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- +1 (866) 930-6790
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AdooQ Bioscience CHINA
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- 025-58849295 18951903616;
- info@adooq.cn