Basic information Safety Supplier Related

FTI-277

Basic information Safety Supplier Related

FTI-277 Basic information

Product Name:
FTI-277
Synonyms:
  • METHYL[N-[2-PHENYL-4-N-[2(R)-AMINO-3-MERCAPTOPROPYLAMINO] BENZOYL]]-METHIONATE, TFA
  • FTI-277
  • N-[4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE METHYL ESTER TRIFLUOROACETATE SALT
  • N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt
  • N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine methyl ester
  • FTI-277;FTI277
  • L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-, methyl ester
CAS:
170006-73-2
MF:
C22H29N3O3S2
MW:
447.61
Mol File:
170006-73-2.mol
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FTI-277 Chemical Properties

Boiling point:
684.2±55.0 °C(Predicted)
Density 
1.222±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: soluble
form 
amorphous semi-solid
pka
9.81±0.10(Predicted)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3

MSDS

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FTI-277 Usage And Synthesis

Uses

Farnesyltransferase inhibitor 277 (FTI-277) has been used to:

  • inhibit protein farnesylation in breast cell lines.
  • in marrow-isolated adult multilineage inducible cells (MIAMI).
  • inhibition of farnesyl transferase in CV-1 in Origin with SV40 genes cells (COS-7).

Biochem/physiol Actions

Farnesyltransferase inhibitor 277 (FTI-277) mediates apoptosis in multiple myeloma and is regarded as a potential therapeutic agent.

FTI-277Supplier

Shanghai Boyle Chemical Co., Ltd.
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Email
sales@boylechem.com
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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3bsc@sina.com
MedChemexpress LLC
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021-58955995
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sales@medchemexpress.cn
AdooQ BioScience, LLC
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+1 (866) 930-6790
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info@adooq.com
AdooQ Bioscience CHINA
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025-58849295 18951903616;
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info@adooq.cn