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Rosuvastatin EP impurity H

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Rosuvastatin EP impurity H Basic information

Product Name:
Rosuvastatin EP impurity H
Synonyms:
  • Rosuvastatin EP impurity H
  • (3R,5RS)-5-[8-uoro-2-[methyl(methylsulfonyl)amino]-4-(propan-2-yl)-5,6- dihydrobenzo[h]quinazolin-6-yl]-3,5-dihydroxypentanoic acid
  • Rosuvastatin calcium EP Impurity H
  • Rosuvastatin Impurity H Sodium Salt (Mixture of Diastereomers)
  • (3R,5RS)-5-[8-Fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl]-3,5-dihydroxypentanoicacid calcium salt
  • Rosuvastatin Impurity QR
  • ppRSV
  • Rosuvastation Impurity H (Calcium salt)
CAS:
1335110-44-5
MF:
C22H28FN3O6S
MW:
481.54
Mol File:
1335110-44-5.mol
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Rosuvastatin EP impurity H Chemical Properties

Boiling point:
719.2±70.0 °C(Predicted)
Density 
1.412±0.06 g/cm3(Predicted)
solubility 
Methanol (Slightly), Water (Slightly)
pka
4.28±0.10(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Rosuvastatin EP impurity H Usage And Synthesis

Uses

(βR,δS)-8-Fluoro-5,6-dihydro-β,δ-dihydroxy-4-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-benzo[h]quinazoline-6-pentanoic Acid Sodium Salt (Rosuvastatin EP Impurity H) is a derived from rosuvastatin, which is a lipid-lowering drug that decomposes under solar irradiation yielding stable dihydrophenanthene analogs.

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