ChemicalBook > Product Catalog > Biochemical Engineering > Inhibitors > Cytoskeletal Signaling > Microtubule Associated inhibitors > Triclabendazole
Triclabendazole
Triclabendazole Basic information
- Product Name:
- Triclabendazole
- Synonyms:
-
- FASINEX
- CGA-89317
- 6-CHLORO-5-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-BENZIMIDAZOLE
- 5-CHLORO-6-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-1H-BENZIMIDAZOLE
- TRICLABENDAZOLE
- 5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1h-benzimidazol
- Tricalbendazole
- 5-Chloro-6-(2,3-dichlorophenoxy)-2-methylthio-1H-benzimidazole, CGA-89317, Fasinex
- CAS:
- 68786-66-3
- MF:
- C14H9Cl3N2OS
- MW:
- 359.66
- EINECS:
- 614-728-7
- Product Categories:
-
- Veterinary drugs
- APIs
- Intermediates & Fine Chemicals
- Pharmaceuticals
- API's
- Pharmaceutical intermediate
- 68786-66-3
- Mol File:
- 68786-66-3.mol
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Triclabendazole Chemical Properties
- Melting point:
- 175-176°C
- Boiling point:
- 240.6°C (rough estimate)
- Density
- 1.3875 (rough estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Acetonitrile (Slightly, Sonicated), Methanol (Slightly)
- form
- Solid
- pka
- 7.91±0.10(Predicted)
- color
- White to Beige
- Merck
- 14,9652
- BCS Class
- 4/3
- Stability:
- Stability
- InChI
- InChI=1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)
- InChIKey
- NQPDXQQQCQDHHW-UHFFFAOYSA-N
- SMILES
- C1(SC)NC2=CC(Cl)=C(OC3=CC=CC(Cl)=C3Cl)C=C2N=1
- CAS DataBase Reference
- 68786-66-3(CAS DataBase Reference)
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Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-24/25
- WGK Germany
- 3
- RTECS
- DD6747000
- HS Code
- 29339900
- Toxicity
- LD50 oral in rabbit: 206mg/kg
MSDS
- Language:English Provider:6-Chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole
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Triclabendazole Usage And Synthesis
Description
Triclabendazole is a benzimidazole anthelmintic. It eliminates both immature and adult flukes in a sheep model of F. hepatica infection when administered at a dose of 10 mg/kg. Triclabendazole (5 μM) also protects against glucose- or α-synuclein-induced apoptosis in S. cerevisiae via inhibition of adenylyl cyclase in the Ras-adenylyl cyclase-protein kinase A (PKA) nutrient sensing pathway.
Chemical Properties
Off-White Solid
Uses
Triclabendazole is classified under the category of ‘Anthelmintic flukicide for veterinary use.
Uses
An anthelmintic (fasciola).
Definition
ChEBI: 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole is an aromatic ether.
TriclabendazoleSupplier
Hubei Yangyi Xinsheng Biological Medicine Co., LTD Gold
- Tel
- 15927387803
- 2263659332@qq.com
Hubei Wanye Zhongcheng Chemical Reagent Co., Ltd. Gold
- Tel
- 18671296875 18671296875
- 1205035102@qq.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 021-61259108 18621169109
- market03@meryer.com
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
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Triclabendazole(68786-66-3)Related Product Information
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- Triclabendazole sulfoxide
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- 5-Chloro-2-mercaptobenzimidazole
- 5-METHOXYBENZIMIDAZOLE
- 1,2,4-Trichlorobenzene
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- 5-HYDROXY-2-MERCAPTO-BENZIMIDAZOLE
- 6-CHLORO-2-(METHYLTHIO)-1H-BENZO[D]IMIDAZOLE