N2-(1-Oxotetradecyl)-L-lysyl-L-alanyl-L-lysyl-L-alaninamide Chemical Properties

Boiling point:

932.2±65.0 °C(Predicted)

Density 

1.060±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

pka

13.43±0.46(Predicted)

Sequence

{Myristoyl-Lys}-Ala-Lys-Ala-NH2

InChIKey

GGEXWRGHXPPRBY-FWEHEUNISA-N

SMILES

C(N)(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)CCCCCCCCCCCCC

N2-(1-Oxotetradecyl)-L-lysyl-L-alanyl-L-lysyl-L-alaninamide Usage And Synthesis

Uses

Myristoyl tetrapeptide-12 directly activates SMAD2 and induces the linking of SMAD3 with DNA. Myristoyl tetrapeptide-12 is capable of stimulating hair growth, especially at the level of eyelashes[1][2].

References

[1] Haeyoung Kwon, et al. Smad-induced alterations of matrix metabolism by a myristoyl tetra peptide. Cell Biochem Funct. 2014 Dec;32(8):665-74. DOI:10.1002/cbf.3070
[2] C. Diehl. Peptides in cosmeceuticals. ISSN 1727-5741 (Print), ISSN 2522-1035 (Online).

N2-(1-Oxotetradecyl)-L-lysyl-L-alanyl-L-lysyl-L-alaninamide(959610-24-3)Related Product Information

• Decapeptide-12
• N2-(1-Oxohexadecyl)-L-lysyl-L-valyl-(2S)-2,4-diaminobutanoyl-L-threonine bis(trifluoroacetate) (salt)
• Dipeptide diaminobutyroyl benzylamide diacetate
• histidyl-arginyl-alanyl-tryptophyl-phenylalanyl-lysinamide
• PALMITOYL TETRAPEPTIDE-3
• Palmitoyl Hexapeptide-12
• Tripeptide-1
• (2S)-N2-(1-Oxohexadecyl)-L-lysyl-L-valyl-2,4-diaminobutanoic acid bis(trifluoroacetate)
• H-Ala-His-Lys-OH
• Myristoyl Hexapeptide-23
• Myristoyl tripeptide-31
• Myristoyl Hexapeptide-16
• Myristoyl Pentapeptide-17
• Myristoyl Dipeptide-13
• Myristoyl Tripeptide-1