Pyrazinecarbonitrile Chemical Properties

Melting point:

18-20°C

Boiling point:

87 °C/6 mmHg (lit.)

Density 

1.174 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.534(lit.)

Flash point:

206 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Acetonitrile (Slightly), Chloroform (Slightly)

pka

-1.97±0.10(Predicted)

form 

Liquid

color 

Clear colorless to yellow

Water Solubility 

Slightly soluble in water.

BRN 

110008

Exposure limits

NIOSH: IDLH 25 mg/m3

InChIKey

PMSVVUSIPKHUMT-UHFFFAOYSA-N

CAS DataBase Reference

19847-12-2(CAS DataBase Reference)

NIST Chemistry Reference

Cyanopyrazine(19847-12-2)

EPA Substance Registry System

2-Cyanopyrazine (19847-12-2)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-36

RIDADR 

3276

WGK Germany 

3

Hazard Note 

Irritant

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29339990

MSDS

• Language:English Provider:Pyrazinecarbonitrile
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Pyrazinecarbonitrile Usage And Synthesis

Chemical Properties

Colorless liquid

Uses

Pyrazinenitrile (Pyrazinamide EP Impurity) is used as a single-source precursor in the synthesis of metal-free nitrogen-doped carbon nanoparticles (NCNPs). Also, it is an important intermediate in the production of pyrazinamide as an effective anti-tubercular drug.

Definition

ChEBI: Cyanopyrazine is a member of pyrazines and a nitrile.

Synthesis

2-cyanopyrazine was prepared from 2-methylpyrazine with iron phosphate catalyst by vapor phase catalytic ammoxidation in a fixed-bed reactor.

Pyrazinecarbonitrile(19847-12-2)Related Product Information

• 3-Chloropyrazine-2-carbonitrile
• 3-AMINO-6-CYANO-5-METHOXY-2-PYRAZINECARBOXIMIDIC ACID, METHYL ESTER
• RARECHEM BG FB 0140
• 2,3-DICYANO-5,6-DIPHENYLPYRAZINE
• 3-AMINO-6-(CHLOROMETHYL)-2-PYRAZINECARBONITRILE-4-,3-AMINO-6-(CHLOROMETHYL)-2-PYRAZINECARBONITRILE 4-OXIDE
• Pyrazinecarbonitrile, 3-amino-6-methyl-, 4-oxide (8CI,9CI),PYRAZINECARBONITRILE, 3-AMINO-6-METHYL-, 4-OXIDE
• 3-AMINO-2-QUINOXALINECARBONITRILE 1,4-DIOXIDE
• 5-ACETOXYMETHYL-2-AMINO-3-CYANOPYRAZINE
• 5,6-DIMETHYL-2,3-PYRAZINEDICARBONITRILE
• 5,6-DICHLORO-2,3-DICYANOPYRAZINE
• 2-AMINO-3-CYANO-5-([(2,4-DICHLORO-5-METHYLPHENYL)THIO]METHYL)PYRAZIN-1-IUM-1-OLATE
• 2-AMINO-3-CYANO-5-PHENYLPYRAZIN-1-IUM-1-OLATE
• 3-AMINO-2-QUINOXALINECARBONITRILE
• 2,3-DICYANO-5-METHYLPYRAZINE
• 2-Amino-3-cyano-5-phenylpyrazine
• Pyrazinecarbonitrile
• Sulfachoropyrazine sodium
• Pyrazinamide