Sodium fluoromethanesulfinate Chemical Properties

storage temp. 

2-8°C, stored under nitrogen

Appearance

Off-white to light yellow Solid

InChI

InChI=1S/CH3FO2S.Na/c2-1-5(3)4;/h1H2,(H,3,4);/q;+1/p-1

InChIKey

VWVSSKREIDWEJT-UHFFFAOYSA-M

SMILES

[Na+].C(F)S([O-])=O

Sodium fluoromethanesulfinate Usage And Synthesis

Uses

Sodium fluoromethanesulfinate is used as efficient radical fluoroalkylating reagents,it is able to react with conjugated N-arylsulfonated amides to yield the desired fluoroalkylamides.

Reactions

Ref. 1) He, Z.; Tan, P.; Ni, C.; Hu, J. Org. Lett. 2015, 17, 1838 –1841. (The invention of HCF2SO2Na and H2CFSO2Na as radical fluoroalkylation reagents)
2) Dai, P.; Yu, X.; Teng, P.; Zhang, W.-H.; Deng, C. Org. Lett. 2018, 20, 6901-6905.
3) Zhang, W. et al. Nat. Commun. 2020, 11, art. no. 638. (HCF2SO2Na was referred to as Hu’s reagent)

Sodium fluoromethanesulfinate(1661836-10-7)Related Product Information

• Fluoromethyl p-toluene sulfide
• Fluoromethylphenylsulfide
• Methanol, fluoro-, benzoate (9CI)
• Potassium trifluoromethanesulfonate
• Disodium methanedisulfonate
• 1H,1H,2H,2H-Perfluorooctanesulfonic acid
• fluorosulfonic acid
• perfluorohexane-1-sulphonic acid