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2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine

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2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine Basic information

Product Name:
2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine
Synonyms:
  • deazaguanine
  • 2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine 7-Deazaguanine
  • 2-amino-1H-pyrrolo[2,3-d]pyrimidin-4-ol
  • 2-Amino-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one
  • 2-AMINO-3,7-DIHYDRO-PYRROLO[2,3-D]PYRIMIDIN-4-ONE
  • 2-AMINO-4-HYDROXY-7H-PYRROLO[2,3-DPYRIMIDINE]
  • 2-AMINO-4-HYDROXYPYRROLO-[2,3-D]PYRIMIDINE
  • 2-AMINO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-OL
CAS:
7355-55-7
MF:
C6H6N4O
MW:
150.14
EINECS:
948-371-6
Product Categories:
  • PYRIMIDINE
  • AMINEPRIMARY
  • Heterocyclic Series
  • Heterocyclic Compounds
  • Bases & Related Reagents
  • Heterocycles
  • Intermediates
  • Nucleotides
Mol File:
7355-55-7.mol
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2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine Chemical Properties

Melting point:
>230°C (dec.)
Density 
1.87±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
Soluble in N,N-Dimethylformamide, Dimethyl sulfoxide.
form 
crystalline
pka
10.83±0.20(Predicted)
color 
tan
CAS DataBase Reference
7355-55-7(CAS DataBase Reference)
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Safety Information

Risk Statements 
36/37/38
Safety Statements 
26-37-60
RIDADR 
2811
WGK Germany 
3
HazardClass 
6.1(a)
PackingGroup 
II
HS Code 
29339900

MSDS

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2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine Usage And Synthesis

Chemical Properties

Pink solid

Uses

Ethidium bromide efficiently intercalates into synthetic duplex DNAs with 7-deazaguanine in place of guanine, but shows none of the fluorescence enhancement usually observed upon intercalation. 7-Deazaadenine-duplexes show about 70% of the expected fluorescence enhancement.

Definition

ChEBI: DG is 7-deazaguanine

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