3-(2-(2-bromoethoxy)ethoxy)prop-1-yne Chemical Properties

storage temp. 

Storage temp. 2-8°C

form 

Liquid

color 

Light yellow to yellow

3-(2-(2-bromoethoxy)ethoxy)prop-1-yne Usage And Synthesis

Uses

Propargyl-PEG2-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

3-(2-(2-bromoethoxy)ethoxy)prop-1-yne(1287660-82-5)Related Product Information

• Propargyl-PEG9-amine
• H2N-PEG2-Propyne
• Propargyl-PEG8-bromide