(LEU31,PRO34)-NEUROPEPTIDE Y (HUMAN, RAT) Chemical Properties

storage temp. 

−20°C

solubility 

Soluble in DMSO

form 

Powder

Water Solubility 

Soluble to 1 mg/ml in water

Sequence

Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2

Safety Information

WGK Germany 

3

MSDS

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(LEU31,PRO34)-NEUROPEPTIDE Y (HUMAN, RAT) Usage And Synthesis

Uses

[Leu31,Pro34]-Neuropeptide Y(human,rat) is a specific neuropeptide Y Y1 receptor agonist. [Leu31,Pro34]-Neuropeptide Y(human,rat) slao activates Y4, Y5. [Leu31,Pro34]-Neuropeptide Y(human,rat) can increase blood pressure in anesthetized rats and increases food intake[1][2].

in vivo

IC 50

NPY Y₁ receptor; NPY Y₄ receptor; NPY Y₅ receptor

storage

Store at -20°C

References

[1] J Fuhlendorff, et al. [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist. Proc Natl Acad Sci U S A. 1990 Jan;87(1):182-6. DOI:10.1073/pnas.87.1.182
[2] K McCrea, et al. 2-36[K4,RYYSA(19-23)]PP a novel Y5-receptor preferring ligand with strong stimulatory effect on food intake. Regul Pept. 2000 Feb 8;87(1-3):47-58. DOI:10.1016/s0167-0115(99)00108-1
[3] A Kask, et al. Evidence for involvement of neuropeptide Y receptors in the regulation of food intake: studies with Y1-selective antagonist BIBP3226. Br J Pharmacol. 1998 Aug;124(7):1507-15. DOI:10.1038/sj.bjp.0701969

(LEU31,PRO34)-NEUROPEPTIDE Y (HUMAN, RAT)(132699-73-1)Related Product Information

• NEUROPEPTIDE Y (HUMAN, RAT)
• PANCREATIC POLYPEPTIDE, RAT
• SUBSTANCE P (2-11)
• SUBSTANCE P (6-11)
• Substance P (1-7)(TFA)
• NEUROPEPTIDE Y (13-36), PORCINE SYNTHETI C >97%
• substance P (3-11)
• Calcitonin Gene Related Peptide (CGRP) (83-119), rat TFA
• Galanin (1-16), mouse, porcine, rat TFA
• NEUROPEPTIDE F
• GALANIN, PORCINE
• GLY-LEU-MET-NH2
• H-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR-NH2
• H-LEU-PRO-GLY-LEU-PRO-SER-ALA-ALA-SER-SER-GLU-ASP-ALA-GLY-GLN-SER-NH2
• SUBSTANCE P (1-9)
• NEUROPEPTIDE FF
• SUBSTANCE P
• ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OME