ISOMITRAPHYLLINE
ISOMITRAPHYLLINE Basic information
- Product Name:
- ISOMITRAPHYLLINE
- Synonyms:
-
- AJMALICIN OXINDOLE A
- (7S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
- 7-Isomitraphylline
- Ajmalicine oxindole A
- ISOMITRAPHYLLINE(SH)
- ISOMITRAPHYLLINE
- Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aS,10'aR)-
- CAS:
- 4963-01-3
- MF:
- C21H24N2O4
- MW:
- 368.43
- Mol File:
- 4963-01-3.mol
ISOMITRAPHYLLINE Chemical Properties
- Boiling point:
- 555.2±50.0 °C(Predicted)
- Density
- 1.33±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- pka
- 13.56±0.60(Predicted)
ISOMITRAPHYLLINE Usage And Synthesis
Description
This Mitragyna alkaloid has been isolated from the leaves of M. speciosa Korth by Beckett and his colleagues. It is an amorphous solid which cannot be obtained crystalline. The base may be characterized as the picrate which forms pale yellow needles from MeOH, m.p. 223°C (dec.). A methylgroup, a methoxycarbonyl group and one imino group are present. The second nitrogen atom is tertiary.
Uses
Isomitraphylline is an oxoindole alkaloid derivied from amazonian plants and maintain medicinal benefits. Used in the treatment of ulcers, arthritis, etc.
References
Beckett et al., J. Pharm. Pharmacol., 17,753 (1965) Beckett et ai., Planta Med., 14, 266 (1966) Structure: Finch, Taylor., J. Amer. Chem. Soc., 84,3871 (1962) Prepara tion: Seaton et al., Can. J. Chem., 38, 1035 (1960)
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