ISOMITRAPHYLLINE Chemical Properties

Boiling point:

555.2±50.0 °C(Predicted)

Density 

1.33±0.1 g/cm3(Predicted)

storage temp. 

-20°C

pka

13.56±0.60(Predicted)

ISOMITRAPHYLLINE Usage And Synthesis

Description

This Mitragyna alkaloid has been isolated from the leaves of M. speciosa Korth by Beckett and his colleagues. It is an amorphous solid which cannot be obtained crystalline. The base may be characterized as the picrate which forms pale yellow needles from MeOH, m.p. 223°C (dec.). A methylgroup, a methoxycarbonyl group and one imino group are present. The second nitrogen atom is tertiary.

Uses

Isomitraphylline is an oxoindole alkaloid derivied from amazonian plants and maintain medicinal benefits. Used in the treatment of ulcers, arthritis, etc.

Biological Activity

Isomitraphylline, an oxindole alkaloid, has potent anti-cancer activity.

References

Beckett et al., J. Pharm. Pharmacol., 17,753 (1965) Beckett et ai., Planta Med., 14, 266 (1966) Structure: Finch, Taylor., J. Amer. Chem. Soc., 84,3871 (1962) Prepara tion: Seaton et al., Can. J. Chem., 38, 1035 (1960)

ISOMITRAPHYLLINE(4963-01-3)Related Product Information

• Oxindole
• ISOMITRAPHYLLINE(P)
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• CHEMBRDG-BB 4002906
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• CHEMBRDG-BB 4002903
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