Zineb Chemical Properties

Melting point:

157°C (rough estimate)

vapor pressure 

<1x l0^-5 at 20 °C

Flash point:

90℃

storage temp. 

2-8°C

solubility 

DMSO (Heated, Very Slightly)

form 

Water-Insoluble Powder

Water Solubility 

ca.10 mg l^-1 (room temperature)

Density 

1.74 g/cm3

Merck 

13,10220

BRN 

4165797

InChIKey

AMHNZOICSMBGDH-UHFFFAOYSA-L

CAS DataBase Reference

12122-67-7(CAS DataBase Reference)

IARC

3 (Vol. 12, Sup 7) 1987

EPA Substance Registry System

Zineb (12122-67-7)

Safety Information

Hazard Codes 

Xi

Risk Statements 

37-43

Safety Statements 

8-24/25-46

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

3

RTECS 

ZH3325000

HazardClass 

6.1

PackingGroup 

III

HS Code 

29309090

Hazardous Substances Data

12122-67-7(Hazardous Substances Data)

Toxicity

LD50 orally in rats: >5000 mg/kg (Gaines)

MSDS

• Language:English Provider:Zinc-ethylenebis(dithiocarbamate)

Zineb Usage And Synthesis

Description

Zineb is a light-coloured powder/crystal and insoluble in water. Zineb is one of the nonsystemic (surface-acting) fungicides of the group ethylenebisdithiocarbamates (EBDCs). Zineb is a polymer of ethylene (bis)thiocarbamate units linked with zinc and used for the control and prevention of crop damage in the field and also to protect harvested crops from deterioration during storage or transport. Zineb was used to protect fruit and vegetable crops from a wide range of foliar and other diseases. It was available in the United States as wettable powder and dust formulations. Zineb can be formed by combining nabam and zinc sulphate in the spray tank.

Chemical Properties

Pure product is white crystal, industrial product is white to light yellow powder. Soluble in carbon disulfide and pyridine, insoluble in most organic solvents, insoluble in water (10mg/L). It is unstable to light, heat and humidity, and decomposes easily when it meets alkaline substances or copper. The decomposition products of zineb include ethylene thiourea, which is more toxic.

Uses

Zineb is a contact fungicide that provides protection against a wide variety of fungal diseases (including leaf spots, blights, rust, downy mildew, scab, etc.) in field crops, fruits, vines, vegetables, ornamentals, citrus and bananas.

Uses

Zineb is a light-colored powder or crystal. It is a polymer of ethylene (bis) thiocarbamate units linked with zinc. Zineb is used to prevent crop damage in the field and to protect harvested crops from deterioration during storage or transport. It was used to protect fruit and vegetable crops from a wide range of foliar and other diseases. It was available in the United States as wettable powder and dust formulations. Zineb can be formed by combining nabam and zinc sulfate in a spray tank.

Definition

ChEBI: Zineb is a polymeric complex of zinc with the ethylene bis(dithiocarbamate) anionic ligand. Formerly used as an agricultural fungicide for the control of downy mildews and rusts, its use is no longer permitted in the US or the EU. It has a role as an antifungal agrochemical. It is a macromolecule, a zinc coordination entity and a dithiocarbamate salt. It contains an ethylenebis(dithiocarbamate).

General Description

An off-white powder. Used as a fungicide.

Air & Water Reactions

Decomposes gradually, accelerated by exposure to air, moisture, and heat. Insoluble in water. Thio and dithiocarbamates slowly decompose in aqueous solution to form carbon disulfide and methylamine or other amines. Such decompositions are accelerated by acids.

Reactivity Profile

Zineb is a zinc salt of a dithiocarbamic acid. May generate flammable gases with aldehydes, nitrides, and hydrides. Incompatible with acids, peroxides, and acid halides.

Hazard

Toxic by inhalation and ingestion; irritant to eyes and mucous membranes. Questionable carcinogen.

Fire Hazard

Flash point data for Zineb are not available, but Zineb is probably combustible.

Contact allergens

Zineb is a pesticide of the dithiocarbamate group. Sensitization can occur in gardeners and florists.

Metabolic pathway

Zineb and other alkylenebis( dithiocarbamate) fungicides are degraded and metabolised via a common pathway. The primary degradation reaction of zineb in water, soil, plants and animals involves the initial dissociation of the metal complex and decomposition to numerous degradation products including ethylenethiourea (ETU) and ethyleneurea (EU) as major products (Scheme 1).

Purification Methods

Crystallise this herbicide several times from hot toluene or from hot CHCl3 by addition of EtOH. It is a skin irritant. [Beilstein 4 III 149, 4 IV 234.]

Degradation

[¹⁴C-ethylene]Zineb(1) was decomposed mainly to ETU (2) in an aqueous suspension after 14 days via the 5,6-dihydro-3H-imidazo[2,1-c]-1,2,4- dithiazole-3-thione (3) intermediate (Vonk, 1976). In dilute alkaline solution and in the presence of light, heat and moisture, zineb decomposed rapidly to compound 3 (Marshall, 1978). ETU (2) in aqueous solutions was further converted into 2-imidazoline (4) and EU (5) (kaars Sijpesteijn and Vonk, 1974). Zineb decomposed in sterile marine culture medium to yield ETU (2) and compound 3. In the presence of copper, an additional degradation product, ethylene diisothiocyanate (6), was also observed (Hunter and Evans, 1991).

Toxicity evaluation

Zineb has a low mammalian toxicity however, it may cause adverse reproduction/developement effects if ingested. It is moderately toxic to most fauna and flora.

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