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FUSARENON X

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FUSARENON X Basic information

Product Name:
FUSARENON X
Synonyms:
  • 4-acetyloxy-12,13-epoxy-3,7,15-trihydroxy-(3-alpha,4-beta,7-beta)-trichothec-9
  • 7-beta)--bet
  • -9-en-8-one
  • -en-8-one
  • Fusarenon
  • Fusarenone X
  • fusarenonex
  • nivalenol-4-o-acetate
CAS:
23255-69-8
MF:
C17H22O8
MW:
354.36
EINECS:
621-752-1
Product Categories:
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Mutagenesis Research Chemicals
  • Pharmaceuticals
  • mycotoxin
Mol File:
23255-69-8.mol
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FUSARENON X Chemical Properties

Melting point:
91-92℃
Boiling point:
407.59°C (rough estimate)
Density 
1.2646 (rough estimate)
refractive index 
1.4430 (estimate)
Flash point:
2 °C
storage temp. 
−20°C
solubility 
Dichloromethane: Soluble
pka
11.70±0.70(Predicted)
CAS DataBase Reference
23255-69-8
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Safety Information

Hazard Codes 
F,Xn,T+
Risk Statements 
11-20/21/22-36-36/37/38-28
Safety Statements 
26-36/37-45-36/37/39-22-16
RIDADR 
3172
WGK Germany 
3
RTECS 
YD0160000
HazardClass 
6.1(a)
PackingGroup 
I
HS Code 
2932990090
Hazardous Substances Data
23255-69-8(Hazardous Substances Data)
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FUSARENON X Usage And Synthesis

Description

Fusarenon X is a type B trichothecene mycotoxin typically derived from Fusarium species. It is primarily found in contaminated cereals. Fusarenon X inhibits protein synthesis, which leads to disruption of DNA synthesis. As this occurs in actively proliferating cells, fusarenon X causes immunosuppression, intestinal malabsorption, developmental toxicity, and genotoxicity. Fusarenon X can be metabolized to fusarenon X-glucoside by infected plants.

Uses

A mycotoxin produced by Fusarium, having immunosuppressive and carcinogenic properties.

Safety Profile

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

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