ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Sulfone, sulfoxide compound > Fenbendazole sulfone
Fenbendazole sulfone
Fenbendazole sulfone Basic information
- Product Name:
- Fenbendazole sulfone
- Synonyms:
-
- FENBENDAZOLE SULFONE
- Carbamic acid, [5-(phenylsulfonyl)-1H-benzimidazol-2-yl]-, methyl ester (9CI)
- HOE 5151
- Methyl [5-(phenylsulfonyl)-1H-benzimidazol-2-yl]carbamate
- oxfendazole sulfone
- [5-(Phenylsulfonyl)-1H-benziMidazol-2-yl]carbaMic Acid Methyl Ester
- Methyl (5-(phenylsulfonyl)-1H-benzo[d]iMidazol-2-yl)carbaMate
- Fenbendazole sulfone solution,100ppm
- CAS:
- 54029-20-8
- MF:
- C15H13N3O4S
- MW:
- 331.35
- Product Categories:
-
- Amines
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
- Sulfur & Selenium Compounds
- Various Metabolites and Impurities
- Metabolites
- Mol File:
- 54029-20-8.mol
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Fenbendazole sulfone Chemical Properties
- Melting point:
- >300°C
- Density
- 1.486±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMF: 10 mg/ml; DMSO: 10 mg/ml
- pka
- 10.14±0.10(Predicted)
- BRN
- 703211
- CAS DataBase Reference
- 54029-20-8
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Fenbendazole sulfone Usage And Synthesis
Description
Fenbendazole sulfone is a minor metabolite of the anthelmintic fenbendazole[1]. Fenbendazole undergoes oxidation to form oxfendazole, which is further oxidized to form fenbendazole sulfone.
Chemical Properties
Pale Pink Solid
Uses
A metabolite of Fenbendazole (F246750).
References
[1] Short, C.R., Flory, W., Hsieh, L.C., et al. The oxidative metabolism of fenbendazole: A comparative study. J. Vet. Pharmacol. Ther. 11(1), 50-55 (1988).
[2] BRETT J. HENRY. Validation of an LC–MS/MS method for assessment of fenbendazole sulfone drug residue in northern bobwhite liver[J]. Biomedical Chromatography, 2023, 37 8. DOI:10.1002/bmc.5637.
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