8-HA-CAMP SODIUM SALT
8-HA-CAMP SODIUM SALT Basic information
- Product Name:
- 8-HA-CAMP SODIUM SALT
- Synonyms:
-
- 8-hexylaminoadenosine-3’,5’-cyclicmonophosphate,sodiumsalt(8-ha-camp)
- 8-HA-CAMP SODIUM SALT
- 8-N-HEXYLAMINOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- Adenosine, 8-(hexylamino)-, cyclic 3',5'-(hydrogen phosphate)
- 8-HA-cAMP
- CAS:
- 59212-44-1
- MF:
- C16H25N6O6P
- MW:
- 428.38
- Mol File:
- 59212-44-1.mol
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8-HA-CAMP SODIUM SALT Usage And Synthesis
Uses
8-HA-cAMP is a membrane-permeable cAMP analogue and an activator of cAMP-dependent protein kinase and PKA I. 8-HA-cAMP exerts metabolic stability towards mammalian cyclic nucleotide-responsive phosphodiesterases[1].
References
[1] Schwede F, et al. 8-Substituted cAMP analogues reveal marked differences in adaptability, hydrogen bonding, and charge accommodation between homologous binding sites (AI/AII and BI/BII) in cAMP kinase I and II. Biochemistry. 2000 Aug 1;39(30):8803-12. DOI:10.1021/bi000304y