15(S)-HEDE Chemical Properties

Boiling point:

475.0±18.0 °C(Predicted)

Density 

0.958±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml

pka

4.78±0.10(Predicted)

15(S)-HEDE Usage And Synthesis

Description

15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC₅₀ value of 26 μM.¹

References

1. Haviv, F., Ratajczyk, J.D., DeNet, R.W., et al. Structural requirements for the inhibition of 5-lipoxygenase by 15-hydroxyeicosa-5,8,11,13-tetraenoic acid analogues J. Med. Chem. 30(2),254-263(1987).

15(S)-HEDE(92693-04-4)Related Product Information

• PD 146176
• CDC
• 5,8,11-EICOSATRIYNOIC ACID
• Caffeic acid
• BW B70C
• Esculetin
• REV 5901
• Baicalein
• 15(S)-HPEDE
• 13(S)-HODE-D4
• 15(S)-HEDE [1-14C]
• 15(S)-HEDE
• (+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID