Nolatrexed
Nolatrexed Basic information
- Product Name:
- Nolatrexed
- Synonyms:
-
- NOLATREXED
- 2-Amino-6-methyl-5-(4-pyridylthio)-4(3H)-quinazolinone
- Nolatrexed [inn]
- NOLA-012
- 4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio)-
- Nolatrexed, 10 mM in DMSO
- CAS:
- 147149-76-6
- MF:
- C14H12N4OS
- MW:
- 284.34
- EINECS:
- 1533716-785-6
- Mol File:
- 147149-76-6.mol
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Nolatrexed Chemical Properties
- Melting point:
- 301-302°
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Nolatrexed Usage And Synthesis
Uses
Nolatrexed (AG 337 free base) is a compound with antifolate activity, high oral bioavailability, and major toxicity at inhibitory doses is gastrointestinal reactions. It can be safely taken orally at specific doses for inhibition, with effects on platelets and neutrophils.
References
[1] Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days PMID:9918208
NolatrexedSupplier
LGM Pharma
- Tel
- 1-(800)-881-8210
- inquiries@lgmpharma.com
BOC Sciences
- Tel
- 16314854226
- info@bocsci.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Lynnchem
- Tel
- 86-(0)29-85992781 17792393971
- info@lynnchem.com
Novachemistry
- Tel
- 44-20819178-90 02081917890
- info@novachemistry.com
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Nolatrexed(147149-76-6)Related Product Information
- Thiophanate-methyl
- 4-Dimethylaminopyridine
- 3-Aminopyridine
- 4-Aminopyridine
- METSULFURON METHYL
- Methyl acetate
- Tribenuron methyl
- 2-Aminopyridine
- Methyl salicylate
- Pirimiphos-methyl
- 2,6-Diaminopyridine
- Kresoxim-methyl
- Methyl
- Parathion-methyl
- Methyl bromide
- Quinazoline
- 2-AMINO-6-METHYL-4(3H)-QUINAZOLONE
- NOLATREXED DIHYDROCHLORIDE,NOLATREXED HCL,NOLATREXED 2HCL