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Nolatrexed

Product Name
Nolatrexed
CAS No.
147149-76-6
Chemical Name
Nolatrexed
Synonyms
NOLA-012;NOLATREXED;Nolatrexed [inn];Nolatrexed, 10 mM in DMSO;2-Amino-6-methyl-5-(4-pyridylthio)-4(3H)-quinazolinone;4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio)-
CBNumber
CB1765629
Molecular Formula
C14H12N4OS
Formula Weight
284.34
MOL File
147149-76-6.mol
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Nolatrexed Property

Melting point:
301-302°
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0005262
Product name
NOLATREXED
Purity
95.00%
Packaging
10MG
Price
$329.7
Updated
2021/12/16
AvaChem
Product number
2072B
Product name
Nolatrexed
Packaging
100mg
Price
$449
Updated
2021/12/16
AvaChem
Product number
2072B
Product name
Nolatrexed
Packaging
5mg
Price
$39
Updated
2021/12/16
AvaChem
Product number
2072B
Product name
Nolatrexed
Packaging
10mg
Price
$59
Updated
2021/12/16
AvaChem
Product number
2072B
Product name
Nolatrexed
Packaging
25mg
Price
$119
Updated
2021/12/16
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Nolatrexed Chemical Properties,Usage,Production

Uses

Nolatrexed (AG 337 free base) is a compound with antifolate activity, high oral bioavailability, and major toxicity at inhibitory doses is gastrointestinal reactions. It can be safely taken orally at specific doses for inhibition, with effects on platelets and neutrophils.

References

[1] Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days PMID:9918208

Nolatrexed Preparation Products And Raw materials

Raw materials

Preparation Products

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Nolatrexed Suppliers

LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Country
China
ProdList
4587
Advantage
58
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.
Tel
027-51831887 15337167856
Fax
027-51837635 QQ1165326703
Email
hubeixinyuanshun@163.com
Country
China
ProdList
10295
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Changzhou Chenhong Biotechnology Co., Ltd.
Tel
+86-0519-85788828 +86-13775037613
Email
sales@chemrenpharm.com
Country
China
ProdList
3934
Advantage
58
Chengdu Peter-like Biotechnology Co., Ltd.
Tel
18108052721
Email
2850505130@qq.com
Country
China
ProdList
5167
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58

147149-76-6, NolatrexedRelated Search:


  • NOLATREXED
  • 2-Amino-6-methyl-5-(4-pyridylthio)-4(3H)-quinazolinone
  • Nolatrexed [inn]
  • NOLA-012
  • 4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio)-
  • Nolatrexed, 10 mM in DMSO
  • 147149-76-6
  • C14H12N4OS