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Nolatrexed

Product Name
Nolatrexed
CAS No.
147149-76-6
Chemical Name
Nolatrexed
Synonyms
NOLA-012;NOLATREXED;Nolatrexed [inn];Nolatrexed, 10 mM in DMSO;2-Amino-6-methyl-5-(4-pyridylthio)-4(3H)-quinazolinone;4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio)-
CBNumber
CB1765629
Molecular Formula
C14H12N4OS
Formula Weight
284.34
MOL File
147149-76-6.mol
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Nolatrexed Property

Melting point:
301-302°
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0005262
Product name
NOLATREXED
Purity
95.00%
Packaging
10MG
Price
$329.7
Updated
2021/12/16
AvaChem
Product number
2072B
Product name
Nolatrexed
Packaging
100mg
Price
$449
Updated
2021/12/16
AvaChem
Product number
2072B
Product name
Nolatrexed
Packaging
5mg
Price
$39
Updated
2021/12/16
AvaChem
Product number
2072B
Product name
Nolatrexed
Packaging
10mg
Price
$59
Updated
2021/12/16
AvaChem
Product number
2072B
Product name
Nolatrexed
Packaging
25mg
Price
$119
Updated
2021/12/16
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Nolatrexed Chemical Properties,Usage,Production

Uses

Nolatrexed (AG 337 free base) is a compound with antifolate activity, high oral bioavailability, and major toxicity at inhibitory doses is gastrointestinal reactions. It can be safely taken orally at specific doses for inhibition, with effects on platelets and neutrophils.

References

[1] Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days PMID:9918208

Nolatrexed Preparation Products And Raw materials

Raw materials

Preparation Products

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Nolatrexed Suppliers

China 18 Europe 2 Germany 1 United Kingdom 3 United States 8 Global 32
ecochem international chemical broker
Tel
--
Fax
--
Email
export@ecochem.dk
Country
Europe
ProdList
6371
Advantage
66
kemikalieimport
Tel
--
Fax
--
Email
Sales@kemikalieimport.dk
Country
Europe
ProdList
6685
Advantage
47

147149-76-6, NolatrexedRelated Search:

Thiophanate-methyl 4-Dimethylaminopyridine 3-Aminopyridine 4-Aminopyridine METSULFURON METHYL Methyl acetate Tribenuron methyl 2-Aminopyridine Methyl salicylate Pirimiphos-methyl 2,6-Diaminopyridine Kresoxim-methyl Methyl Parathion-methyl Methyl bromide Quinazoline 2-AMINO-6-METHYL-4(3H)-QUINAZOLONE NOLATREXED DIHYDROCHLORIDE,NOLATREXED HCL,NOLATREXED 2HCL

  • NOLATREXED
  • 2-Amino-6-methyl-5-(4-pyridylthio)-4(3H)-quinazolinone
  • Nolatrexed [inn]
  • NOLA-012
  • 4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio)-
  • Nolatrexed, 10 mM in DMSO
  • 147149-76-6
  • C14H12N4OS