3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile
3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile Basic information
- Product Name:
- 3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile
- Synonyms:
-
- 3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile
- 3-(O-CHLOROPHENYL)-3-HYDROXY-3-PHENYL PROPIONITRILE
- 1-(o-Chlorophenyl)-2-cyano-1-phenyl-ethenol
- 2-Chloro-hydroxy-phenyl benzene-propanenitrile
- 3-(2-chlorophenyl)-3-hydroxy-3-phenylpropanenitrile
- Benzenepropanenitrile, 2-chloro-β-hydroxy-β-phenyl-
- CAS:
- 35173-29-6
- MF:
- C15H12ClNO
- MW:
- 257.71
- EINECS:
- 252-419-5
- Mol File:
- 35173-29-6.mol
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3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile Chemical Properties
- Melting point:
- 90-92 °C
- Boiling point:
- 482.0±40.0 °C(Predicted)
- Density
- 1.253±0.06 g/cm3(Predicted)
- pka
- 11.82±0.29(Predicted)
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3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile Usage And Synthesis
Chemical Properties
Crystalline compounds. Melting point 88-91 ℃.
Uses
3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile is the intermediate of the enemy cough.
Synthesis
Use o-chlorobenzoic acid to chlorinate with thionyl chloride to generate o-chlorobenzoyl chloride, which is then condensed with benzene under the participation of aluminum trichloride to obtain o-chlorobenzoyl. 3-(O-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile is obtained by condensing the latter with acetonitrile under the action of sodium amide.
3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrile Preparation Products And Raw materials
Raw materials
3-(o-chlorophenyl)-3-hydroxy-3-phenylpropiononitrileSupplier
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