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cephaeline hydrochloride

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cephaeline hydrochloride Basic information

Product Name:
cephaeline hydrochloride
Synonyms:
  • cephaelin hydrochloride
  • Cephaeline dihydrochloride
  • (1R)-1-[[(2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-6-isoquinolinol hydrochloride
  • NSC 32944
  • Cephaeline HCl salt
  • (-)-CEPHAELINE DIHYDROCHLORIDE
  • Cephaeline hydrochloride CRS
  • Cephaeline DiHCl
CAS:
5853-29-2
MF:
C28H39ClN2O4
MW:
503.08
EINECS:
227-463-3
Mol File:
5853-29-2.mol
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cephaeline hydrochloride Chemical Properties

storage temp. 
4°C, protect from light
solubility 
Soluble in DMSO
form 
Solid
color 
White to off-white
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Safety Information

RIDADR 
1544
HazardClass 
6.1(b)
PackingGroup 
III
Toxicity
LD50 oral in mouse: 74970ug/kg
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cephaeline hydrochloride Usage And Synthesis

Chemical Properties

Off-white to yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from ipecac, Angola anise maple.

Uses

Epichenol hydrochloride can kill the trophozoites of lysosomes and is toxic.

Biological Activity

Cephaeline dihydrochloride is a selective CYP2D6 inhibitor with IC50 of 121 μM.

target

IC50: 121 μM (CYP2D6)
Ki: 54 μM (CYP2D6)

cephaeline hydrochlorideSupplier

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