ChemicalBook > Product Catalog > API > Digestive system drugs > Emetics and antiemetics > cephaeline
cephaeline
cephaeline Basic information
- Product Name:
- cephaeline
- Synonyms:
-
- cephaeline
- O-Phosphatidyl-ethanolamine
- Cefalin
- (-)-Cephaelin
- (1R)-1-[[(2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-6-isoquinolinol
- 7',10,11-Trimethoxyemetan-6'-ol
- Cepheline
- Desmethylemetine
- CAS:
- 483-17-0
- MF:
- C28H38N2O4
- MW:
- 466.61
- EINECS:
- 207-591-6
- Product Categories:
-
- Chiral Reagents
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 483-17-0.mol
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cephaeline Chemical Properties
- Melting point:
- 115-1160C
- alpha
- D20 -43.4° (c = 2 in chloroform)
- Boiling point:
- 569.42°C (rough estimate)
- Density
- 1.21±0.1 g/cm3 (20 ºC 760 Torr)
- refractive index
- 1.5800 (estimate)
- storage temp.
- -20°C Freezer
- solubility
- Acetonitrile: slightly soluble; Chloroform: slightly soluble; Ethanol: slightly soluble; Methanol: slightly soluble
- form
- A crystalline solid
- pka
- 9.90±0.40(Predicted)
- color
- Light yellow to yellow
- Stability:
- Hygroscopic
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cephaeline Usage And Synthesis
Chemical Properties
Crystalline Solid
Uses
Has been used as an emetic and expectorant
Uses
Cephaeline occurs in the ground roots ofipecac along with emetine. The Brazilian variety usually contains about 0.5%cephaeline. It is used as an emetic and anti amebic reagent.
Definition
ChEBI: A pyridoisoquinoline comprising emetam having a hydroxy group at the 6'-position and methoxy substituents at the 7'-, 10- and 11-positions.
Health Hazard
The toxicity of cephaeline is lower than thatof emetine. The toxic effects are cumula tive. Ingestion of high doses may producehypotension, muscle weakness, and gastroin testinal problems, including nausea, vomiting, and diarrhea.
cephaelineSupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 021-61259108 18621169109
- market03@meryer.com
Chemsky(shanghai)International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
Chengdu Biopurify Phytochemicals Ltd.
- Tel
- +86-028-82633397 18982077548
- cwb1@biopurify.cn
Shanghai Kewel Chemical Co., Ltd.
- Tel
- 021-64609169 18901607656
- greensnown@163.com
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cephaeline(483-17-0)Related Product Information
- VERATRINE
- MINIMALE LIEFERMENGE
- L-Hyoscyamine
- Xanthiazone
- EMETINE HCL
- menisdaurin
- daurisoline
- ISOEMETINE HYDROBROMIDE
- veratramine
- VERATRIDINE
- Xanthiside
- EMETINE HYDROBROMIDE
- CEPHAELINE HYDROCHLORIDE
- Emetine
- Cephaeline dihydrochloride
- methylpsychotrine
- CEPHAELINE DIHYDROCHLORIDE N X 2 HCL
- CEPHAELINE HYDROBROMIDE (200 MG)