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CEPHAELINE HYDROCHLORIDE

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CEPHAELINE HYDROCHLORIDE Basic information

Product Name:
CEPHAELINE HYDROCHLORIDE
Synonyms:
  • CEPHAELINE HYDROCHLORIDE
  • CEPHAELINE HYDROCHLORIDE USP/EP/BP
  • Cephaeline hydrochloride,virus,Influenza Virus,Zika,alkaloid,Filovirus,Cephaeline,Ebola,Inhibitor,phenolic,inhibit,NSC 32944 monohydrochloride
  • Cephaeline hydrochloride, 10 mM in DMSO
CAS:
3738-70-3
MF:
C28H40Cl2N2O4
MW:
539.53
Mol File:
3738-70-3.mol
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CEPHAELINE HYDROCHLORIDE Usage And Synthesis

Uses

Cephaeline hydrochloride ((-)-Cephaeline hydrochloride) is a phenolic alkaloid in Indian Ipecac roots. Cephaeline hydrochloride exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections[1][2].

IC 50

EBOV

References

[1] N.P.Sahu, et al. Determination of emetine and cephaeline in Ipecac roots by high- performance liquid chromatography. Journal of Chromatography A. 1982 Apr; 238( 2):525-529.
[2] Yang S, et al. Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry. Cell Discov. 2018 Jun 5;4:31. DOI:10.1038/s41421-018-0034-1

CEPHAELINE HYDROCHLORIDESupplier

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ALB Technology Limited
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