5beta-Cholan-3alpha,7alpha,24-triol CAS#: 23848-46-6

5beta-Cholan-3alpha,7alpha,24-triol Basic information

Product Name:

5beta-Cholan-3alpha,7alpha,24-triol

Synonyms:

Reaxys ID: 2285975
CDC-OH
UDC-OH
Reaxys ID: 4472691
3α,7α,24-Trihydroxy-5β-cholan
Chenodeoxycholan-24-ol
5β-CHOLAN-3α, 7α, 24-TRIOL

CAS:

23848-46-6

MF:

C24H42O3

MW:

378.59

Mol File:

23848-46-6.mol

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5beta-Cholan-3alpha,7alpha,24-triol Chemical Properties

Boiling point:: 509.5±25.0 °C(Predicted)
Density: 1.079±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: Dichloromethane;
form: Solid
pka: 14.79±0.70(Predicted)
color: Off-white Foamy

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5beta-Cholan-3alpha,7alpha,24-triol Usage And Synthesis

Uses

Chenodeoxycholan-24-ol is an intermediate used in the synthesis of 3α,7α-Dihydroxycoprostanic Acid-d3 (D452517), which is a labelled analogue of 3α,7α-Dihydroxycoprostanic Acid (D452515), a precursor of Cholic Acid (C432600), it undergoes side chain oxidation during the synthesis of bile acids. It was found that Zellweger’s syndrome patients have abnormal mitochondrial structure, the organelle that is responsible for the side chain oxidation, and as a consequence, excess amounts of 3α,7α-Dihydroxycoprostanic Acid.

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