CHOLIC-2,2,4,4-D4 ACID
CHOLIC-2,2,4,4-D4 ACID Basic information
- Product Name:
- CHOLIC-2,2,4,4-D4 ACID
- Synonyms:
-
- Cholic-d4 Acid
- Cholic acid-2,2,4,4-d
- 5β-cholanic acid-3α,7α,12α-triol-2,2,4,4-d4
- CHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
- Cholic Acid -[d4] (Solution)
- Cholic Acid-d4 MaxSpec? Standard
- 2H4]-Cholic Acid
- CHOLICACID(2,2,4,4-D4) IN METHANOL
- CAS:
- 116380-66-6
- MF:
- C24H36D4O5
- MW:
- 412.6
- Product Categories:
-
- Steroids & Hormones - 13C & 2H
- Mol File:
- 116380-66-6.mol
CHOLIC-2,2,4,4-D4 ACID Chemical Properties
- Melting point:
- 200-201°C (lit.)
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml
- form
- Solid
- color
- White to Off-White
CHOLIC-2,2,4,4-D4 ACID Usage And Synthesis
Description
Cholic acid-d4 is intended for use as an internal standard for the quantification of cholic acid by GC- or LC-MS. Cholic acid is a primary bile acid. It is formed from cholesterol via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. Cholic acid is conjugated to glycine or taurine by bile acid-CoA:amino acid N-acyltransferase (BAAT) to produce glycocholic acid (GCA; ) and taurocholic acid (TCA; ), respectively, in the liver, and is transformed into the secondary bile acid deoxycholic acid (DCA; ) by intestinal microbiota. It induces C. difficile colony formation in an agar dilution assay when used at a concentration of 0.1% w/v. Dietary administration of cholic acid (0.4% w/w) increases serum cholesterol levels, biliary phospholipid secretion, and fecal DCA levels in rats.
Uses
Cholic Acid-d4 is a labelled analog of Cholic acid (C432600) which is a choleretic produced by, and isolated from liver cells.
Definition
ChEBI: Cholic acid-2,2,4,4-d4 is a bile acid.
CHOLIC-2,2,4,4-D4 ACIDSupplier
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CHOLIC-2,2,4,4-D4 ACID(116380-66-6)Related Product Information
- DEOXYCHOLIC-2,2,4,4-D4 ACID
- Ursodeoxycholic acid
- 5beta-Cholan-3alpha,7alpha,24-triol
- Sodium deoxycholate
- Sodium cholate
- 5-BETA-CHOLANIC ACID-7-ALPHA, 12-ALPHA-DIOL
- CHOLIC-2,2,4,4-D4 ACID
- OCTADECANOIC-12-D1 ACID
- CHENODEOXYCHOLIC-2,2,4,4-D4 ACID
- HEXADECANOIC-12-D1 ACID
- LITHOCHOLIC-2,2,4,4-D4 ACID
- HEXADECANOIC-13,13-D2 ACID
- TETRADECANOIC-12-D1 ACID