Basic information Safety Supplier Related

CHOLIC-2,2,4,4-D4 ACID

Basic information Safety Supplier Related

CHOLIC-2,2,4,4-D4 ACID Basic information

Product Name:
CHOLIC-2,2,4,4-D4 ACID
Synonyms:
  • Cholic-d4 Acid
  • Cholic acid-2,2,4,4-d
  • 5β-cholanic acid-3α,7α,12α-triol-2,2,4,4-d4
  • CHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
  • Cholic Acid -[d4] (Solution)
  • Cholic Acid-d4 MaxSpec? Standard
  • 2H4]-Cholic Acid
  • CHOLICACID(2,2,4,4-D4) IN METHANOL
CAS:
116380-66-6
MF:
C24H36D4O5
MW:
412.6
Product Categories:
  • Steroids & Hormones - 13C & 2H
Mol File:
116380-66-6.mol
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CHOLIC-2,2,4,4-D4 ACID Chemical Properties

Melting point:
200-201°C (lit.)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml
form 
Solid
color 
White to Off-White
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Safety Information

WGK Germany 
3
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CHOLIC-2,2,4,4-D4 ACID Usage And Synthesis

Description

Cholic acid-d4 is intended for use as an internal standard for the quantification of cholic acid by GC- or LC-MS. Cholic acid is a primary bile acid. It is formed from cholesterol via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. Cholic acid is conjugated to glycine or taurine by bile acid-CoA:amino acid N-acyltransferase (BAAT) to produce glycocholic acid (GCA; ) and taurocholic acid (TCA; ), respectively, in the liver, and is transformed into the secondary bile acid deoxycholic acid (DCA; ) by intestinal microbiota. It induces C. difficile colony formation in an agar dilution assay when used at a concentration of 0.1% w/v. Dietary administration of cholic acid (0.4% w/w) increases serum cholesterol levels, biliary phospholipid secretion, and fecal DCA levels in rats.

Uses

Cholic Acid-d4 is a labelled analog of Cholic acid (C432600) which is a choleretic produced by, and isolated from liver cells.

Definition

ChEBI: Cholic acid-2,2,4,4-d4 is a bile acid.

CHOLIC-2,2,4,4-D4 ACIDSupplier

ChemeGen(Shanghai) Biotechnology Co.,Ltd. Gold
Tel
18818260767
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sales@chemegen.com
Shanghai Beiwanta Biotechnology Co., Ltd. Gold
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021-67187366 19901745723
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info@bwtlab.com
Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-400-6206333 18521732826
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market@aladdin-e.com
Clearsynth Labs Limited
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+91-22-26355700
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info@clearsynth.com
TianJin Alta Scientific Co., Ltd.
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022-65378550-8551
Email
contact@altascientific.com