HYOCHOLIC ACID Chemical Properties

Melting point:

162 °C

Boiling point:

565.7±40.0 °C(Predicted)

Density 

1.184±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Ethanol (Slightly), Methanol (Slightly, Heated)

form 

Solid

pka

4.76±0.10(Predicted)

color 

Light Brown to Brown

optical activity

+5.525

HYOCHOLIC ACID Usage And Synthesis

Uses

3α,6α,7α-Trihydroxy-5β-cholanic Acid is one of the bile acids categorizes under muricholic acid, a group of bile acids found in human urine due to its additional hydroxyl groups. The synthesis of 3α,6α,7α-Trihydroxy-5β-cholanic Acid was shown to be promoted due to overexpression of cholesterol 7α-hydroxylase enzyme.

Definition

ChEBI: A trihydroxy-5beta-cholanic acid in which the three hydroxy substituents are located at the 3alpha-, 6alpha- and 7alpha-positions.

Biological Activity

Hyocholic acid levels are elevated in plasma and urine samples of patients with cholestatic liver disease and in hepatic cirrhosis.

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