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Hyodeoxycholic acid

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Hyodeoxycholic acid Basic information

Product Name:
Hyodeoxycholic acid
Synonyms:
  • 7-deoxyhyocholicacid
  • alpha-hyodeoxycholicacid
  • 3α,6α-Dihydroxy-5β-cholanoic acid
  • Hyodeoxycholic
  • 3à,6à-dihydroxy-5á-cholan-24-oic acid
  • 3a,6a-Dihydroxy-5b-Cholan-24-Oic Acid
  • HYODEOXYCHOLIC ACID FREE ACID
  • HYODEOXYCHOLIC ACID 98%
CAS:
83-49-8
MF:
C24H40O4
MW:
392.58
EINECS:
201-483-2
Product Categories:
  • Inhibitors
  • reference standards from Chinese medicinal herbs (TCM).
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Herb extract
  • standardized herbal extract
  • Natural Plant Extract
  • Metabolites & Impurities
  • Pharmaceuticals
  • Steroids
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
Mol File:
83-49-8.mol
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Hyodeoxycholic acid Chemical Properties

Melting point:
200-201 °C (lit.)
alpha 
D20 +8° (alc)
Boiling point:
437.26°C (rough estimate)
Density 
0.9985 (rough estimate)
refractive index 
1.4460 (estimate)
storage temp. 
Refrigerator
solubility 
Solubility in methanol, very faint turbidity. Slightly soluble in alcohol, acetone, ether and very slightly soluble in chloroform.
pka
4.76±0.10(Predicted)
form 
Solid
color 
White to Off-White
Water Solubility 
5.889mg/L(25 ºC)
Merck 
14,4857
InChIKey
DGABKXLVXPYZII-SIBKNCMHSA-N
CAS DataBase Reference
83-49-8(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
36/37/38-40
Safety Statements 
26-36/37/39-36-22-37
WGK Germany 
3
RTECS 
FZ2050000
HS Code 
29181990

MSDS

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Hyodeoxycholic acid Usage And Synthesis

Chemical Properties

White Solid

Uses

Protected β-Hyodeoxycholic Acid (H998105), a potential bile acid metabolite.

Uses

Labelled Hyodeoxycholic Acid. Unlabelled version is isolated from pig bile. Antitumor agent

Uses

It is isolated from pig bile. Antitumor agent

Uses

Labelled β-Hyodeoxycholic Acid

Definition

ChEBI: A member of the class of 5beta-cholanic acids that is (5beta)-cholan-24-oic acid substituted by alpha-hydroxy groups at positions 3 and 6.

General Description

Hyodeoxycholic acid is a naturally occurring secondary bile acid. It is produced by the gut flora in the small intestine. Hyodeoxycholic acid is obtained from chenodeoxycholic acid during enterohepatic circulation of bile in rats.

Purification Methods

Crystallise -hyodeoxycholic acid from EtOAc or Me2CO. The K salt separates in needles from an alcoholic solution of the acid when an equivalent of KOMe is added (see lithocholic acid). [Weiland & Gumlish Hoppe Seyler's Z Physiol Chem 215 18 1933, Windaus & Bohne Justus Liebigs Ann Chem 433 278 1923, Beilstein 10 III 1631.]

Hyodeoxycholic acid Preparation Products And Raw materials

Raw materials

Hyodeoxycholic acid Supplier

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