Basic information Safety Supplier Related

5,10-Methylene-THF

Basic information Safety Supplier Related

5,10-Methylene-THF Basic information

Product Name:
5,10-Methylene-THF
Synonyms:
  • 5,10-Methylene-THF
  • (6R) 5,10-Methylenetetrahydrofolate
  • 5,10-Methylene-THF// (S)-2-(4-((R)-3-Amino-1-oxo-5,6,6a,7-tetrahydro imidazo[1,5-f]pteridin-8(1H,4H,9H)-yl)benzami do)pentanedioic acid
  • N5,N10-Methylene-5,6,7,8-tetrahydrofolate
  • (S)-2-(4-((R)-3-amino-1-oxo
  • (S)-2-(4-((R)-3-Amino-1-oxo-5,6,6a,7-tetrahydroimidazo[1,5-f]pteridin-8(1H,4H,9H)-yl)benzamido)pentanedioic acid
  • L-Glutamic acid, N-[4-[(6aR)-3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl]-
  • Folinic Acid EP Impurity I
CAS:
31690-11-6
MF:
C20H23N7O6
MW:
457.44
Mol File:
31690-11-6.mol
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5,10-Methylene-THF Chemical Properties

Density 
1.75±0.1 g/cm3(Predicted)
pka
3.47±0.10(Predicted)
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5,10-Methylene-THF Usage And Synthesis

Uses

Arfolitixorin is a folate prodrug that is used in the treatment for colorectal cancer as a way for increase in efficacy and reducing the side effects of antimetabolites used in cancer treatment.

Definition

ChEBI: (6R)-5,10-methylenetetrahydrofolic acid is the (6R)-stereoisomer of 5,10-methylenetetrahydrofolic acid. It has a role as an Escherichia coli metabolite, a mouse metabolite and a cofactor. It is a conjugate acid of a (6R)-5,10-methylenetetrahydrofolate(2-).

5,10-Methylene-THFSupplier

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