5,10-Methylene-THF
5,10-Methylene-THF Basic information
- Product Name:
- 5,10-Methylene-THF
- Synonyms:
-
- 5,10-Methylene-THF
- (6R) 5,10-Methylenetetrahydrofolate
- 5,10-Methylene-THF// (S)-2-(4-((R)-3-Amino-1-oxo-5,6,6a,7-tetrahydro imidazo[1,5-f]pteridin-8(1H,4H,9H)-yl)benzami do)pentanedioic acid
- N5,N10-Methylene-5,6,7,8-tetrahydrofolate
- (S)-2-(4-((R)-3-amino-1-oxo
- (S)-2-(4-((R)-3-Amino-1-oxo-5,6,6a,7-tetrahydroimidazo[1,5-f]pteridin-8(1H,4H,9H)-yl)benzamido)pentanedioic acid
- L-Glutamic acid, N-[4-[(6aR)-3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl]-
- Folinic Acid EP Impurity I
- CAS:
- 31690-11-6
- MF:
- C20H23N7O6
- MW:
- 457.44
- Mol File:
- 31690-11-6.mol
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5,10-Methylene-THF Chemical Properties
- Density
- 1.75±0.1 g/cm3(Predicted)
- pka
- 3.47±0.10(Predicted)
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5,10-Methylene-THF Usage And Synthesis
Uses
Arfolitixorin is a folate prodrug that is used in the treatment for colorectal cancer as a way for increase in efficacy and reducing the side effects of antimetabolites used in cancer treatment.
Definition
ChEBI: (6R)-5,10-methylenetetrahydrofolic acid is the (6R)-stereoisomer of 5,10-methylenetetrahydrofolic acid. It has a role as an Escherichia coli metabolite, a mouse metabolite and a cofactor. It is a conjugate acid of a (6R)-5,10-methylenetetrahydrofolate(2-).
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