8-methyladenosine
8-methyladenosine Basic information
- Product Name:
- 8-methyladenosine
- Synonyms:
-
- 8-methyladenosine
- Adenosine, 8-methyl-
- (2R,3R,4S,5R)-2-(6-Amino-8-methyl-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
- 8-Methyladenosine, RNA modified nucleoside m8A
- CAS:
- 56973-12-7
- MF:
- C11H15N5O4
- MW:
- 281.27
- Mol File:
- 56973-12-7.mol
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8-methyladenosine Usage And Synthesis
Uses
8-Methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Definition
ChEBI: 8-Methyladenosine is a purine nucleoside.
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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