8-METHYLTHIOGUANOSINE Chemical Properties

Density 

2.12±0.1 g/cm3(Predicted)

pka

9.17±0.20(Predicted)

8-METHYLTHIOGUANOSINE Usage And Synthesis

Uses

8-(Methylthio)guanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

References

[1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100

8-METHYLTHIOGUANOSINE(2104-66-7)Related Product Information

• 8-methylguanosine
• Adenosine,8-(methylthio)- (7CI,8CI,9CI)
• 8-methyladenosine