Basic information Safety Supplier Related

Adenosine,8-(methylthio)- (7CI,8CI,9CI)

Basic information Safety Supplier Related

Adenosine,8-(methylthio)- (7CI,8CI,9CI) Basic information

Product Name:
Adenosine,8-(methylthio)- (7CI,8CI,9CI)
Synonyms:
  • Adenosine,8-(methylthio)- (7CI,8CI,9CI)
  • Adenosine, 8-(methylthio)-
  • (2R,3R,4S,5R)-2-(6-amino-8-(methylthio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
CAS:
29836-01-9
MF:
C11H15N5O4S
MW:
313.33
Mol File:
29836-01-9.mol
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Adenosine,8-(methylthio)- (7CI,8CI,9CI) Chemical Properties

Melting point:
235-237 °C
Boiling point:
704.4±70.0 °C(Predicted)
Density 
1.98±0.1 g/cm3(Predicted)
pka
12.99±0.70(Predicted)
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Adenosine,8-(methylthio)- (7CI,8CI,9CI) Usage And Synthesis

Uses

8-Methylthio-adenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

References

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020

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