Adenosine,8-(methylthio)- (7CI,8CI,9CI)
Adenosine,8-(methylthio)- (7CI,8CI,9CI) Basic information
- Product Name:
- Adenosine,8-(methylthio)- (7CI,8CI,9CI)
- Synonyms:
-
- Adenosine,8-(methylthio)- (7CI,8CI,9CI)
- Adenosine, 8-(methylthio)-
- (2R,3R,4S,5R)-2-(6-amino-8-(methylthio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
- CAS:
- 29836-01-9
- MF:
- C11H15N5O4S
- MW:
- 313.33
- Mol File:
- 29836-01-9.mol
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Adenosine,8-(methylthio)- (7CI,8CI,9CI) Chemical Properties
- Melting point:
- 235-237 °C
- Boiling point:
- 704.4±70.0 °C(Predicted)
- Density
- 1.98±0.1 g/cm3(Predicted)
- pka
- 12.99±0.70(Predicted)
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Adenosine,8-(methylthio)- (7CI,8CI,9CI) Usage And Synthesis
Uses
8-Methylthio-adenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
References
[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
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