Basic information Safety Supplier Related

8-SHOGAOL

Basic information Safety Supplier Related

8-SHOGAOL Basic information

Product Name:
8-SHOGAOL
Synonyms:
  • 8-ShogaoI
  • (E)-1-(4-hydroxy-3-methoxyphenyl)dodec-4-en-3-one
  • 8-SHOGAOL
  • 1-(4-Hydroxy-3-methoxyphenyl)-4-dodecen-3-one
  • 4-Dodecen-3-one, 1-(4-hydroxy-3-methoxyphenyl)-
  • 1-(4-Hydroxy-3-methoxyphenyl)dodec-4-en-3-one
  • 8-gingerenol
  • 8-Shogaol-RM
CAS:
36700-45-5
MF:
C19H28O3
MW:
304.42
EINECS:
200-258-5
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
36700-45-5.mol
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8-SHOGAOL Chemical Properties

Boiling point:
452.3±35.0 °C(Predicted)
Density 
1.013±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in chloroform and methanol;
pka
10.01±0.20(Predicted)
form 
liquid
color 
Colorless - yellowish viscous
Water Solubility 
insoluble in water
InChI
InChI=1S/C19H28O3/c1-3-4-5-6-7-8-9-10-17(20)13-11-16-12-14-18(21)19(15-16)22-2/h9-10,12,14-15,21H,3-8,11,13H2,1-2H3
InChIKey
LGZSMXJRMTYABD-UHFFFAOYSA-N
SMILES
C(C1=CC=C(O)C(OC)=C1)CC(=O)C=CCCCCCCC
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8-SHOGAOL Usage And Synthesis

Chemical Properties

Slightly soluble in methanol, soluble in petroleum ether, ethyl acetate, chloroform. Derived from the rhizome of ginger.

Uses

8-?Shogaol is a component of ginger (Zingiber officinale) and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.

Definition

ChEBI: [8]-Shogaol is a monomethoxybenzene, an enone and a member of phenols.

in vivo

[8]-Shogaol (10 mg/kg, 30 mg/kg; ip; once daily for 10 days) reduces paw thickness and improves walking performance in a rat model of adjuvant-induced arthritis (AIA)[4].

target

ROS

IC 50

COX-2: 17.5 μM (IC50)

8-SHOGAOLSupplier

Shanghai Yingxin Laboratory Equipment Co., Ltd. Gold
Tel
021-59178156 17002132182
Email
3146474380@qq.com
Shanghai Fuorain BioTech Co., Ltd Gold
Tel
18672534757
Email
xiaoxue.hu@fuorain.cn
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Email
cwb1@biopurify.cn
Shanghai Winherb Medical Technology Co., Ltd.
Tel
021-38218169 13341702378
Email
winherb@126.com
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Email
tauto@tautobiotech.com
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