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BENAZEPRILAT
BENAZEPRILAT Basic information
- Product Name:
- BENAZEPRILAT
- Synonyms:
-
- BENAZEPRILAT
- BENAZEPRILAT HCL HYDRATE
- Benazepril hydrochloride impurity C
- Benazepril Impurity 3(Benazepril EP Impurity C)
- (3S)-3-[[(S)-1-Carboxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid
- CGS-14831
- Benazepril Related Compound C (50 mg) ((3S)-3-[[(1S)-1- carboxy-3-phenylpropyl]amino-2,3,4,5-tetrahydro-2-oxo- 1H-1-benzazepine]-1-acetic acid)
- (3S)-3-[[(1S)-1-carboxy-3-phenylpropyl]aMino-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine]-1-acetic acid
- CAS:
- 86541-78-8
- MF:
- C22H24N2O5
- MW:
- 396.44
- Product Categories:
-
- Intermediates & Fine Chemicals
- Metabolites
- Pharmaceuticals
- Aromatics
- Heterocycles
- Metabolites & Impurities
- Chiral Reagents
- Mol File:
- 86541-78-8.mol
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BENAZEPRILAT Chemical Properties
- Melting point:
- 270-272°C
- alpha
- D -200.5° (c = 1 in 3% aqueous NH4OH)
- Boiling point:
- 711.3±60.0 °C(Predicted)
- Density
- 1.34±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- solubility
- Aqueous Base (Slightly), DMSO (Slightly)
- form
- Solid
- pka
- 2.17±0.10(Predicted)
- color
- White to Off-White
- CAS DataBase Reference
- 86541-78-8
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BENAZEPRILAT Usage And Synthesis
Chemical Properties
Crystalline Solid
Uses
Benazeprilat is a metabolite of Benazepril, which is used as an antihypertensive.
Definition
ChEBI: A benzazepine that is 1,3,4,5-tetrahydro-2H-1-benzazepin-2-one in which the hydrogen attached to the nitrogen is replaced by a carboxy methyl group and in which the 3-pro-S hydrogen is replaced by the amino roup of (2S)-2-amino-4-phenylbutanoic acid. An angiotensin-converting enzyme inhibitor, it is used as its monoester prodrug benazepril in the treatment of hypertension and heart failure.
BENAZEPRILATSupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
Sinopharm Chemical Reagent Co,Ltd.
- Tel
- 86-21-63210123
- sj_scrc@sinopharm.com
Wisdom Pharmaceutical Co., Ltd.
- Tel
- 0086-15189180296
- l_xu@wisdompharma.com
Cato Research Chemicals Inc.
- Tel
- 020-81960175
- min.he@cato-chem.com
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BENAZEPRILAT(86541-78-8)Related Product Information
- CGP 14829A
- (S)-3-AMino-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic Acid
- BENAZEPRIL-D5 HYDROCHLORIDE
- Benazepril-(17a)
- Benazepril-(S,R)
- BENAZEPRILAT-D5
- Benazepril Impurity 1 (Benazepril Methyl Ester)
- S-ATBA
- Benazepril hydrochloride
- BENAZEPRILAT
- BENAZEPRIL-D5
- Benazeprilat Acyl--D-glucuronide
- BENAZEPRIL TERT-BUTYL ESTER D5
- Benazeprilat-d5 Acyl--D-glucuronide
- BENAZEPRIL RELATED COMPOUND A (15 MG) ((3R)-3-[[(1 R)-1 -(ETHOXYCARBONYL)-3-PHENYLPROPYL]AMI-NO]-2,3,4,5-TETRAHYDRO-2-OXO-1 H-1 -BENZAZEPINE-1-ACETIC ACID, MONOHYDROCHLORIDE)
- BENAZEPRILAT MM(CRM STANDARD)
- BENAZEPRILAT MM
- BENAZEPRIL RELATED COMPOUND B (15 MG) ((3S)-3-[[(1 R)-1 -(ETHOXYCARBONYL)-3-PHENYLPROPYL]AMI-NO]-2,3,4,5-TETRAHYDRO-2-OXO-1 H-1 -BENZAZEPINE-1-ACETIC ACID, MONOHYDROCHLORIDE)