2-PIPERIDIN-4-YL-1H-BENZOIMIDAZOLE Chemical Properties

Melting point:

230 °C (decomp)(Solv: water (7732-18-5))

Boiling point:

441.3±38.0 °C(Predicted)

Density 

1.167±0.06 g/cm3(Predicted)

vapor pressure 

0Pa at 25℃

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

soluble in Methanol

form 

Solid

pka

11.83±0.10(Predicted)

color 

White to Light yellow to Light orange

λmax

279nm(MeOH)(lit.)

Safety Information

Hazard Codes 

Xi

HS Code 

2933.99.8290

HazardClass 

IRRITANT

2-PIPERIDIN-4-YL-1H-BENZOIMIDAZOLE Usage And Synthesis

Uses

2-Piperidin-4-yl-1H-benzimidazole is used as a reagent in the synthesis of 3-amino-1-(5-indanyloxy)-2-propanol derivatives as potent sodium channel blockers for the treatment of ischemic stroke. Also used as a reagent in the synthesis of 2,3,5-trisubstituted pyridine derivatives as potent Akt1/Akt2 dual inhibitors.

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