2-(BENZYLOXY)-ETHYLAMINE Chemical Properties

Boiling point:

241℃

Density 

1.45

refractive index 

1.5260

Flash point:

85℃

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

Chloroform (Slightly), DMSO (Slightly)

form 

Oil

pka

8.82±0.10(Predicted)

color 

Colourless to Pale Yellow

InChI

InChI=1S/C9H13NO/c10-6-7-11-8-9-4-2-1-3-5-9/h1-5H,6-8,10H2

InChIKey

XJGVVOAKITWCAB-UHFFFAOYSA-N

SMILES

C(N)COCC1=CC=CC=C1

Safety Information

RIDADR 

3267

HazardClass 

8

PackingGroup 

III

HS Code 

2921599090

2-(BENZYLOXY)-ETHYLAMINE Usage And Synthesis

Uses

2-(Benzyloxy)-1-ethanamine (2-(Benzyloxy)ethylamine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis Reference(s)

Tetrahedron Letters, 36, p. 3465, 1995 DOI: 10.1016/0040-4039(95)00527-J

Synthesis

GENERAL METHOD: Compound (CAS: 87107-79-7) (3 mmol) was dissolved in ethanol (30 mL) at 50 °C, followed by slow addition of 85% hydrazine hydrate (0.19 mL, 3.3 mmol). The reaction temperature was maintained at 50 °C and the reaction mixture was stirred continuously for 4 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the solids were separated by filtration. The filtrate was concentrated under reduced pressure to give the crude product 2-(benzyloxy)ethylamine in 90% yield.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 14, p. 2782 - 2787
[2] Patent: WO2012/64680, 2012, A1. Location in patent: Page/Page column 142
[3] Patent: WO2012/62157, 2012, A1. Location in patent: Page/Page column 142; 143
[4] Patent: US2011/178077, 2011, A1. Location in patent: Page/Page column 14

2-(BENZYLOXY)-ETHYLAMINE(38336-04-8)Related Product Information

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• Z-SER(BZL)-OH
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• Benoxinate Hydrochloride
• O-BENZYL-DL-SERINE
• BENZOYLCHOLINE CHLORIDE
• 4-Methoxy-alpha-methyl-N-(phenylmethyl)benzeneethanamine
• Benzyltriethylammonium chloride
• N-BENZYLDIETHYLAMINE
• HEMICHOLINIUM-3
• 4-BENZYLIDENE-2-PHENYL-2-OXAZOLIN-5-ONE
• 2',3',5'-TRI-O-BENZOYLINOSINE
• N,N-Dimethyl-2-(alpha-(o-tolyl)benzyloxy)ethylamine hydrochloride
• 2-(2-CHLORO-BENZYLOXY)-ETHYLAMINE HYDROCHLORIDE