HEMICHOLINIUM-3
HEMICHOLINIUM-3 Basic information
- Product Name:
- HEMICHOLINIUM-3
- Synonyms:
-
- 2,2’-(1,1’-biphenyl)-4,4’-diylbis(2-hydroxy-4,4-dimethyl-morpholinium)dibrom
- 2,2’-(4,4’-biphenylylene)bis(2-hydroxy-4,4-dimethyl-morpholiniudibromide
- hc-3
- hemicholine
- hemicholinium-3bromide
- hemicholinium-3dibromide
- hemicholiniumbromide
- hemicholiniumdibromide
- CAS:
- 312-45-8
- MF:
- C24H34N2O4.2Br
- MW:
- 574.351
- EINECS:
- 206-227-3
- Mol File:
- 312-45-8.mol
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HEMICHOLINIUM-3 Chemical Properties
- Melting point:
- 180°; mp 226- 228° (dec)
- storage temp.
- Store at -20°C
- solubility
- ethanol: 1.3 mg/mL
- form
- solid
- color
- white
- Water Solubility
- Water : 33.33 mg/mL (58.03 mM; Need ultrasonic)
- Merck
- 13,4660
- BRN
- 5704458
- EPA Substance Registry System
- Morpholinium, 2,2'-[1,1'-biphenyl]-4,4'-diylbis[2-hydroxy-4,4-dimethyl-, dibromide (312-45-8)
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Safety Information
- Hazard Codes
- T
- Risk Statements
- 23/24/25-36/37/38
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 2811 6.1/PG 2
- WGK Germany
- 3
- RTECS
- QF2450000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Toxicity
- LD50 i.p. in female mice: 0.048-0.082 mg/kg (DiAugustine, Haarstad)
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HEMICHOLINIUM-3 Usage And Synthesis
Uses
Acetylcholine stores depletor
Uses
Hemicholinium-3 has been used in the preparation of Krebs-HC-3 buffer to study its effects on choline uptake and choline acetyltransferase activity in differentiated human neuroblastoma (SK-N-SH) cells.
Uses
Research tool as cholinergic probe, to deplete acetylcholine stores.
Biochem/physiol Actions
Hemicholinium-3 plays a role in blocking the neuronal choline uptake thereby inhibiting acetylcholine synthesis in the brain.
HEMICHOLINIUM-3Supplier
Shanghai Aladdin Bio-Chem Technology Co.,LTD
- Tel
- 400-400-6206333 18521732826
- market@aladdin-e.com
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Shanghai Chaolan Chemical Technology Center
- Tel
- 021-QQ：65489617 15618227136
- Sales@ATKchemical.com
Angel Pharmatech, Ltd.
- Tel
- 17317130613
- 3358272972@qq.com
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HEMICHOLINIUM-3(312-45-8)Related Product Information
- 4,4'-Bis(hydroxymethyl)biphenyl
- 2-Methylmorpholine
- 4-Biphenylmethanol
- 4-Ethylbiphenyl
- 2-(4-BIPHENYL)ETHYLAMINE
- 4,4'-Dimethylbiphenyl
- 4-Methylphenethylamine
- 1-(4-Methylphenyl)ethanol
- DL-ALPHA-(METHYLAMINOMETHYL)BENZYL ALCOHOL
- N-Methyldiethanolamine
- 2-(BENZYLOXY)-ETHYLAMINE
- 4,4'-Bis(methoxymethyl)-1,1'-biphenyl
- 1-(4-BIPHENYLYL)ETHANOL
- CHOLINE BROMIDE
- N,N-Dimethylphenethylamine
- BIPHENYLENE
- 4,4'-DIETHYLBIPHENYL
- 2-PHENYLMORPHOLINE