4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE Chemical Properties

Melting point:

94-96 °C (dec.)(lit.)

Boiling point:

357.77°C (rough estimate)

Density 

1.2160 (rough estimate)

refractive index 

1.5560 (estimate)

storage temp. 

2-8°C

pka

-2.59±0.20(Predicted)

form 

Solid

color 

Gray to brown

Water Solubility 

Soluble in methanol (50 mg/ml), and water (partly).

BRN 

163055

CAS DataBase Reference

15646-46-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

43

Safety Statements 

36

WGK Germany 

3

RTECS 

RQ5786250

HazardClass 

IRRITANT

HS Code 

29349990

Toxicity

mouse,LD50,intravenous,56mg/kg (56mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#06780,

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE Usage And Synthesis

Chemical Properties

white to orange or pink powder

Uses

4-Ethoxymethylene-2-phenyloxazolin-5-one acts as sensitizing agent. It is also used as pharmaceutical intermediates.

Uses

4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression studies of the two forms of inflammatory bowel disease like Crohn′s disease and ulcerative colitis.

Definition

ChEBI: A 1,3-oxazole compound having a phenyl substituent at the 2-position, an ethoxymethylene group at the 4-position, and an oxo group at the 5-position. It is a chemical allergen used for immunological experiments, particularly for experiments on delayed typ hypersensitivity.

4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE(15646-46-5)Related Product Information

• 2-Ethoxyethylamine
• 2-(BENZYLOXY)-ETHYLAMINE
• Ethyl vinyl ether
• Methoxyethene
• Ethyl acrylate
• 2-PHENYL-5-OXAZOLONE
• 2-METHYL-2-OXAZOLINE
• N-BENZYLIDENEMETHYLAMINE
• 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE
• ALLYL METHYL ETHER
• 3-ETHOXYACRYLIC ACID
• Ethyl propenyl ether
• 4,5-DIHYDRO-2-PHENYLOXAZOLE
• ACRYLATE, AMMONIUM
• Allyl Benzyl Ether
• H-Gly-OBzl
• Benzyl acrylate
• 1-Methoxy-1-propene